Marian S.
- Country
- Slovakia
- Department
- Onkologická klinika
Research Overview
- Efficacy Comparison of Zanzalintinib (XL092) and Pembrolizumab Versus Pembrolizumab Monotherapy in PD-L1 Positive Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma
- Phase 2 Randomized Double-Blind Placebo-Controlled Study of Ponsegromab in Cancer Cachexia with Elevated GDF-15 Concentrations
- Efficacy of Volrustomig (MEDI5752) Plus Chemotherapy Versus Pembrolizumab Plus Chemotherapy in Metastatic Non-Small Cell Lung Cancer with PD-L1 < 1%
Data & Insights
Has run more than one trial at 245 of 485 partner sites.
Specializations
Lung Cancer Research
Specializes in advanced treatment approaches for non-small cell lung cancer (NSCLC), with particular focus on cases involving HER2 mutations and metastatic disease. Investigation includes targeted therapies and combination treatments for patients with varying PD-L1 expression levels.
- Advanced NSCLC with HER2 mutations
- Metastatic NSCLC treatment strategies
- Immunotherapy combinations
Breast Cancer Innovation
Focuses on developing treatments for hormone receptor-positive, HER2-negative breast cancer in both advanced and metastatic settings. Investigates novel therapeutic combinations involving targeted therapies and hormonal treatments.
- Advanced/metastatic breast cancer
- Hormone receptor-positive disease
- Endocrine therapy resistance
Specialized Oncology Areas
Conducts research in diverse oncological conditions including metastatic castration-resistant prostate cancer, cancer cachexia, and head and neck squamous cell carcinoma. Explores innovative treatment approaches for complex cancer presentations.
- Prostate cancer therapeutics
- Cancer-related cachexia
- Head and neck cancer treatments
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