Marian G.
- Country
- Spain
- Department
- Nephorogy Service
Research Overview
- A Phase I Dose Escalation Study of Bispecific Antibodies in Adult Patients with Lupus Nephritis
- AN OPEN-LABEL STUDY TO EVALUATE THE SAFETY AND PHARMACOKINETICS OF MIGALASTAT HCL IN SUBJECTS WITH FABRY DISEASE AND AMENABLE GLA VARIANTS AND SEVERE RENAL IMPAIRMENT OR END-STAGE RENAL DISEASE TREATED WITH HEMODIALYSIS
- Evaluation of Colchicine and Tiemonium Methylsulphate in Secondary Prevention of Cardiovascular Events in Moderate Chronic Renal Disease Patients
Data & Insights
Has run more than one trial at 9 of 61 partner sites.
Specializations
Nephrology and Renal-Associated Disorders
Clinical research activity in nephrology includes a strong focus on kidney disease and conditions linked to renal impairment, with involvement across chronic and immune-mediated renal disorders.
- Chronic Kidney Disease
- IgA Nephropathy
- Lupus Nephritis
- Kidney Transplant
- End-Stage Kidney Disease
Research interest also extends to renal complications associated with systemic disease, including cardiovascular and metabolic comorbidity in patients with impaired kidney function.
Hematology and Blood Malignancies
Research involvement covers a broad spectrum of hematologic malignancies and marrow disorders, with emphasis on therapies for both newly diagnosed and relapsed disease.
- Multiple Myeloma
- Acute Myeloid Leukemia
- Myelodysplastic Syndromes
- Diffuse Large B-Cell Lymphoma
- Chronic Lymphocytic Leukemia
The investigator is also linked to studies in lymphoma, myelofibrosis, and immune cytopenias, reflecting a therapeutic interest in complex blood cancers and related hematologic conditions.
Solid Tumors and Precision Oncology
Clinical trial activity includes extensive work in oncology, especially across advanced solid tumors and biomarker-defined cancers treated with targeted and immunologic approaches.
- Non-Small Cell Lung Cancer
- Breast Cancer
- Colorectal Cancer
- Renal Cell Carcinoma
- Hepatocellular Carcinoma
Additional involvement spans pancreatic cancer, biliary tract cancer, melanoma, and urothelial carcinoma, with attention to molecular targets such as EGFR, KRAS, and HER2.
Autoimmune, Inflammatory, and Immune-Mediated Disease
Research interests include immune-driven disorders affecting the skin, joints, connective tissue, and gastrointestinal tract, alongside systemic autoimmune disease.
- Systemic Lupus Erythematosus
- Rheumatoid Arthritis
- Psoriatic Arthritis
- Inflammatory Bowel Disease
- Atopic Dermatitis
Therapeutic activity also includes hidradenitis suppurativa, psoriasis, Sjogren’s syndrome, and scleroderma, with a clear emphasis on immune modulation.
Cardiometabolic, Hepatic, and Respiratory Conditions
The investigator is involved in trials addressing cardiovascular disease, metabolic dysfunction-associated steatohepatitis, and chronic respiratory illness, indicating a broad internal medicine profile.
- Heart Failure
- Atherosclerotic Cardiovascular Disease
- Obesity
- Cholestatic Liver Disease
- Chronic Obstructive Pulmonary Disease
Related interests include primary biliary cholangitis, idiopathic pulmonary fibrosis, and asthma, with clinical attention to chronic organ dysfunction and inflammation.
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