Maria T. S.
- Country
- Spain
- Department
- Hepatology
Research Overview
Data & Insights
Has run more than one trial at 0 of 58 partner sites.
Specializations
Chronic Liver Disease & Fibrosis
The investigator concentrates on progressive chronic liver disease and the mechanisms driving liver fibrosis in diverse patient populations.
- cirrhosis
- fibrotic remodeling
- portal hypertension
Research aims to identify biomarkers that reflect disease severity and predict clinical outcomes.
Hepatocellular Carcinoma & Liver Oncology
Focused on malignant transformation within the liver, the work addresses hepatocellular carcinoma and related primary liver cancers.
- tumor microenvironment
- early detection
- therapeutic resistance
Efforts include evaluating novel targets that may improve survival in advanced disease.
Metabolic Liver Disorders (NAFLD/NASH)
The investigator explores metabolic dysfunction leading to non‑alcoholic fatty liver disease and its progressive form, non‑alcoholic steatohepatitis.
- insulin resistance
- lipid accumulation
- inflammatory signaling
Studies aim to delineate pathways that link obesity, diabetes, and liver injury.
Autoimmune Hepatic Conditions
Research includes immune‑mediated liver diseases such as primary biliary cholangitis and autoimmune hepatitis, emphasizing pathogenic auto‑antibodies and immune regulation.
- antimitochondrial antibodies
- immune tolerance
- fibroinflammatory pathways
Goals are to refine diagnostic criteria and identify therapeutic windows.
Cardiovascular Co‑Morbidity in Liver Patients
Recognizing the interplay between liver health and heart disease, the work investigates atherosclerotic cardiovascular disease and associated lipid abnormalities in hepatic cohorts.
- lipoprotein(a) elevation
- vascular inflammation
- cardiac outcomes
Findings support integrated management strategies for patients with dual organ risk.
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