Maria Sole C.
- Country
- Italy
- Department
- Rheumatology Unit
Research Overview
- Long-Term Safety, Tolerability, and Efficacy of Zasocitinib in Adults With Active Psoriatic Arthritis: A Phase 3 Extension Study
- Phase 3 Randomized Double‑Blind Placebo‑Controlled Study of Enpatoran for Active Cutaneous Lupus Erythematosus (with or without systemic disease)
- Efficacy and Safety of Subcutaneous Guselkumab in Bio-naive Patients with Active Psoriatic Arthritis Axial Disease: A Phase 4 Randomized, Double-blind, Placebo-controlled Study
Data & Insights
Has run more than one trial at 92 of 188 partner sites.
Specializations
Rheumatology and autoimmune disease
Clinical research activity is centered in rheumatology, with strong involvement in inflammatory disorders that affect joints, skin, and systemic immune pathways.
- Psoriatic arthritis
- Hidradenitis suppurativa
- Systemic inflammation
- Immune-mediated disease
The therapeutic landscape includes conditions linked to chronic immune dysregulation and biologic treatment development in inflammatory disease.
Inflammatory bowel disease
Research involvement extends to major gastroenterology indications, especially chronic intestinal inflammation and symptom control in active disease.
- Crohn’s disease
- Ulcerative colitis
- Bowel urgency
- Transmural healing
This area reflects interest in therapies aimed at controlling intestinal inflammation, improving mucosal outcomes, and addressing persistent disease burden.
Neurology and neuroimmunology
Clinical trial activity includes neurological disorders with a pronounced focus on chronic immune-mediated and degenerative conditions.
- Multiple sclerosis
- Parkinson’s disease
- Myasthenia gravis
- Epilepsy
The therapeutic scope also includes treatment strategies for relapsing and progressive neurological disease, together with symptom-focused neurological care.
Dermatology and allergic disease
Research interests cover inflammatory skin disease, pruritic disorders, and immune-related dermatologic conditions requiring targeted therapy.
- Plaque psoriasis
- Atopic dermatitis
- Prurigo nodularis
- Chronic inducible urticaria
This domain includes both chronic inflammatory skin disease and allergic manifestations driven by immune activation.
Hematology and oncology
Trial activity also spans blood cancers and related marrow disorders, with emphasis on therapies for progressive and treatment-resistant disease.
- Acute myeloid leukemia
- Myelodysplastic syndromes
- Chronic lymphocytic leukemia
- Prostate cancer
The portfolio includes malignancies with hematologic and solid-tumor relevance, reflecting engagement in advanced therapeutic innovation across oncology.
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