Melinda K.
- Country
- Romania
- Department
- Cardiologie
Research Overview
Data & Insights
Has run more than one trial at 72 of 555 partner sites.
Specializations
Cardiovascular disease and heart failure
Dan Luchian is involved in clinical research centered on atherosclerotic cardiovascular disease, atrial fibrillation, acute myocardial infarction, hypertension, and heart failure, with interest in prevention of recurrent ischemic and thromboembolic events.
- Stroke prevention in atrial fibrillation
- Cardiovascular risk reduction
- Heart failure with kidney impairment
- Acute coronary syndromes
His work also includes therapies aimed at reducing cardiovascular events in patients with established disease or high cardiometabolic risk.
Liver disease and metabolic dysfunction
His research landscape includes non-alcoholic steatohepatitis, metabolic dysfunction-associated steatotic liver disease, and overweight or obesity with type 2 diabetes, reflecting a strong therapeutic focus on metabolic liver disorders.
- NASH with fibrosis
- MASLD
- Weight management in diabetes
- Liver histology and clinical liver outcomes
He is active in studies addressing progression of fatty liver disease alongside metabolic and cardiovascular comorbidity.
Oncology and lung cancer
As a medical oncology investigator, Dan Luchian is engaged in studies of non-small cell lung cancer, including tumors with uncommon EGFR mutations, as well as HER2-positive breast cancer.
- NSCLC after surgery
- Uncommon EGFR-mutated lung cancer
- HER2-positive metastatic breast cancer
- Post-treatment disease control
His trial portfolio also extends to immuno-oncology and targeted treatment strategies in solid tumors.
Inflammatory bowel disease and gastrointestinal inflammation
His clinical research includes ulcerative colitis, with attention to therapies for moderately to severely active disease and induction of clinical response.
- Ulcerative colitis
- Intestinal inflammation
- Clinical remission
- Maintenance of disease control
This area adds a gastrointestinal dimension to his broader therapeutic involvement.
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