María M. G.
- Country
- Spain
- Department
- Pneumonology
Research Overview
- A Phase 3, Randomized, Double-blind, Placebo-controlled Study to Evaluate the Efficacy and Safety of Admilparant in Participants with Progressive Pulmonary Fibrosis
- Efficacy and Safety of BI 1015550 in Individuals with Interstitial Lung Abnormalities and a Family History of Pulmonary Fibrosis: A Randomized, Placebo-Controlled Trial
- A study to evaluate the safety and effectiveness of inhaled nintedanib in patients with idiopathic pulmonary fibrosis
Data & Insights
Has run more than one trial at 166 of 301 partner sites.
Specializations
Pulmonary Infections and Chronic Airway Disease
Clinical research activity includes nontuberculous mycobacterial lung infection, chronic obstructive pulmonary disease, asthma, bronchiectasis, and community-acquired and hospital-acquired pneumonia, with particular attention to difficult-to-control respiratory conditions.
- Idiopathic pulmonary fibrosis and other interstitial lung diseases
- Pulmonary sarcoidosis and progressive pulmonary fibrosis
- Severe asthma with eosinophilic inflammation
- Chronic cough and allergic rhinitis
Work in this area also extends to respiratory syncytial virus prevention and infection-related lung complications.
Cardiovascular and Thromboembolic Disease
The investigator is involved in studies on atrial fibrillation, acute myocardial infarction, heart failure, atherosclerotic cardiovascular disease, and stroke prevention, including conditions linked to elevated cardiovascular risk.
- Heart failure with preserved or reduced ejection fraction
- Atrial fibrillation and cardioembolic risk
- Acute ischemic stroke and transient ischemic attack
- Lipoprotein(a) and severe hypertriglyceridemia
Therapeutic interests also include amyloid cardiomyopathy and vascular risk reduction in patients with complex cardiometabolic profiles.
Autoimmune, Inflammatory, and Immune-Mediated Disorders
Research involvement covers systemic lupus erythematosus, lupus nephritis, psoriatic arthritis, rheumatoid arthritis, myositis, and IgG4-related disease, reflecting a strong focus on immune-driven disease.
- Systemic sclerosis-associated interstitial lung disease
- Dermatomyositis and polymyositis
- Chronic spontaneous urticaria and atopic dermatitis
- Thyroid eye disease and uveitis
The portfolio also includes hidradenitis suppurativa, vitiligo, and other chronic inflammatory skin and systemic conditions.
Kidney, Transplantation, and Metabolic Disease
Clinical interests include chronic kidney disease, IgA nephropathy, end-stage renal disease, kidney transplant rejection, and renal allograft dysfunction, alongside metabolic disorders that influence renal and cardiovascular outcomes.
- Kidney transplantation and antibody-mediated rejection
- Focal segmental glomerulosclerosis and membranous nephropathy
- Type 2 diabetes and obesity
- Severe hypertriglyceridemia and metabolic dysfunction-associated steatotic liver disease
Additional activity includes Fabry disease and transthyretin amyloidosis with renal or systemic involvement.
Oncology and Hematologic Malignancies
Research participation spans non-small cell lung cancer, breast cancer, colorectal cancer, prostate cancer, and urothelial carcinoma, together with multiple blood cancers and advanced solid tumors.
- Multiple myeloma and myelodysplastic syndromes
- Diffuse large B-cell lymphoma and chronic lymphocytic leukemia
- Melanoma and head and neck squamous cell carcinoma
- Gastric cancer and pancreatic adenocarcinoma
Therapeutic interests also extend to advanced and metastatic malignancies with molecularly defined targets.
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