Maria Lucia B. V.
- Country
- Spain
- Department
- Digestive system
Research Overview
- Evaluation of Reactogenicity, Safety, Immunogenicity, and Efficacy of GSK HBV Viral Vector and Adjuvanted Protein Vaccines in Chronic Hepatitis B Patients
- Phase 3 Randomized, Double-Blind, Placebo-Controlled Study of Lanifibranor in Adults with Non-Cirrhotic Non-Alcoholic Steatohepatitis and Fibrosis Stages F2/F3
- Safety and Tolerability Assessment of Dostarlimab in Adults with Chronic Hepatitis B on Nucleos(t)ide Analogue Therapy
Data & Insights
Has run more than one trial at 9 of 98 partner sites.
Specializations
Breast cancer and endocrine-driven tumors
María Lucía Bonet Vidal is involved in clinical research focused on breast cancer, with attention to HER2-positive breast cancer, HER2-negative breast cancer, triple-negative breast cancer, and hormone receptor-positive disease across early, locally advanced, and metastatic settings. Her trial activity also extends to endocrine therapy, PIK3CA-mutated tumors, and recurrence-risk management in breast oncology.
- HER2-positive breast cancer
- Triple-negative breast cancer
- Endocrine therapy in ER-positive/HER2-negative disease
- PIK3CA-mutated breast cancer
- Early and metastatic breast cancer
Her research landscape includes therapeutic interest in neoadjuvant, adjuvant, and metastatic breast cancer treatment, with a strong emphasis on biomarker-linked strategies and disease control.
Hematologic malignancies
She is active in studies of acute myeloid leukemia, acute lymphoblastic leukemia, multiple myeloma, lymphoma, and myelodysplastic syndrome, covering both newly diagnosed and relapsed or refractory disease. This area also includes interest in pediatric leukemia and high-risk hematologic cancers.
- Acute myeloid leukemia
- Acute lymphoblastic leukemia
- Multiple myeloma
- Lymphoma
- Myelodysplastic syndrome
Her clinical research involvement reflects a therapeutic focus on hematologic oncology, including disease settings that require novel approaches for resistant or high-risk presentations.
Thoracic oncology and solid tumors
Her trial portfolio includes extensive work in non-small cell lung cancer, small cell lung cancer, renal cell carcinoma, ovarian cancer, endometrial cancer, cervical cancer, colorectal cancer, and urothelial cancer. She is also connected to research in head and neck cancer, prostate cancer, and other advanced solid tumors.
- Non-small cell lung cancer
- Small cell lung cancer
- Renal cell carcinoma
- Gynecologic cancers
- Urothelial cancer
Her research interests center on advanced solid tumors and malignancies with limited treatment options, especially where targeted or immune-based strategies are being explored.
Respiratory, cardiovascular, and metabolic disease
María Lucía Bonet Vidal also participates in studies of chronic obstructive pulmonary disease, asthma, idiopathic pulmonary fibrosis, pulmonary arterial hypertension, and systemic sclerosis-associated interstitial lung disease. Her non-oncology interests include atherosclerotic cardiovascular disease, acute ischemic stroke, heart failure-related risk, obesity, and type 2 diabetes.
- Chronic obstructive pulmonary disease
- Idiopathic pulmonary fibrosis
- Pulmonary arterial hypertension
- Atherosclerotic cardiovascular disease
- Obesity and type 2 diabetes
Her clinical research landscape spans chronic cardiopulmonary and metabolic conditions where long-term disease modification and symptom control remain central therapeutic goals.
Immune-mediated, infectious, and gastrointestinal disorders
She is also involved in trials addressing ulcerative colitis, Crohn's disease, psoriasis, hidradenitis suppurativa, lupus nephritis, and IgA nephropathy. Additional interest is seen in HIV infection, hepatitis B, latent tuberculosis infection, bacteremia, and other serious infections.
- Inflammatory bowel disease
- Psoriasis and hidradenitis suppurativa
- Lupus nephritis
- HIV infection
- Latent tuberculosis infection
Her research activity includes therapeutic interest in immune-mediated inflammation, chronic infection, and organ-specific complications affecting the digestive, renal, and dermatologic domains.
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