María José S.
- Country
- Spain
- Department
- Nefrología
Research Overview
- A Phase 3, Multicenter, Randomized, Double-blind, Placebo-controlled Trial to Evaluate the Efficacy and Safety of Sibeprenlimab Administered Subcutaneously in Subjects with Immunoglobulin A Nephropathy
- Efficacy and Safety of Balcinrenone and Dapagliflozin Versus Dapagliflozin in Adults with Chronic Kidney Disease and Albuminuria: A Randomized, Double-Blind Study
- Efficacy and Safety Evaluation of BI 764198 in Patients with Focal Segmental Glomerulosclerosis: A Randomized, Double-Blind, Placebo-Controlled Trial
Data & Insights
Has run more than one trial at 42 of 182 partner sites.
Specializations
Thoracic Oncology
Clinical research activity includes non-small cell lung cancer, small cell lung cancer, metastatic lung cancer, and other advanced thoracic malignancies, with emphasis on biomarker-defined disease and treatment-resistant settings.
- Non-small cell lung cancer
- Small cell lung cancer
- ALK, EGFR, and KRAS-altered disease
- Head and neck squamous cell carcinoma
Work in this area also extends to mesothelioma, esophageal cancer, and other advanced solid tumors treated in precision oncology programs.
Breast and Gynecologic Oncology
Research involvement covers breast cancer across hormone receptor-positive, HER2-positive, and triple-negative subtypes, together with recurrent and metastatic tumors of the ovary, endometrium, cervix, and fallopian tube.
- Hormone receptor-positive breast cancer
- HER2-positive breast cancer
- Triple-negative breast cancer
- Ovarian cancer
The portfolio includes endometrial cancer, cervical cancer, and gastroesophageal junction adenocarcinoma when managed within advanced solid tumor programs.
Hematologic Malignancies
Clinical trial activity includes a broad spectrum of blood cancers, with particular focus on lymphoma, acute myeloid leukemia, multiple myeloma, and chronic lymphoid disorders.
- Diffuse large B-cell lymphoma
- Chronic lymphocytic leukemia
- Multiple myeloma
- Myelodysplastic syndromes
Additional interests include mantle cell lymphoma, follicular lymphoma, Waldenström macroglobulinemia, and graft-versus-host disease in transplant-related care.
Autoimmune and Inflammatory Disease
Investigational work spans immune-mediated disorders such as systemic lupus erythematosus, rheumatoid arthritis, psoriatic arthritis, and Sjögren's disease, alongside other chronic inflammatory conditions.
- Systemic lupus erythematosus
- Rheumatoid arthritis
- Psoriatic arthritis
- Myasthenia gravis
Research also includes systemic sclerosis, juvenile idiopathic arthritis, inflammatory myopathies, and inflammatory bowel disease.
Metabolic, Renal, and Cardiovascular Disorders
Clinical interests also cover chronic kidney disease, renal cell carcinoma, heart failure, atherosclerotic cardiovascular disease, and obesity-related complications.
- Chronic kidney disease
- Renal cell carcinoma
- Heart failure
- Obesity
Additional therapeutic areas include diabetes mellitus, liver disease, pulmonary arterial hypertension, and sleep apnea.
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