Maria Jesus D. C. M.
- Country
- Spain
- Department
- Cardiology
Research Overview
- Evaluation of Sotatercept (MK-7962) Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics in Pediatric Pulmonary Arterial Hypertension
- Long-term Evaluation of Sotatercept in Combination with Background Therapy for Pulmonary Arterial Hypertension in Adult Patients
- Pharmacokinetics, Safety, and Efficacy of Macitentan Versus Standard Care in Pediatric Pulmonary Arterial Hypertension: A Multicenter, Open-Label, Randomized Study
Data & Insights
Has run more than one trial at 50 of 74 partner sites.
Specializations
Pediatric Cardiology
The investigator is based in pediatric cardiology, with clinical trial activity centered on cardiovascular disease in children and adolescents, including congenital and acquired heart conditions, rhythm disorders, and structural heart disease management.
- Congenital heart disease
- Pulmonary arterial hypertension
- Heart failure
- Cardiomyopathy
Research interest also extends to cardiovascular risk reduction and pediatric cardiac complications that require specialized therapeutic monitoring.
Inflammatory and Autoimmune Disease
Clinical research involvement includes immune-mediated disorders affecting joints, connective tissue, and the skin, with attention to chronic inflammatory disease control and symptom relief.
- Juvenile idiopathic arthritis
- Systemic lupus erythematosus
- Sjögren’s disease
- Behçet’s disease
Additional therapeutic interest is seen in conditions such as thyroid eye disease, bullous pemphigoid, and other immune-driven disorders.
Neuroimmunology and Neuromuscular Disorders
The investigator is also engaged in research on neurological diseases with immune or degenerative mechanisms, including disorders that affect motor function, muscle strength, and central nervous system inflammation.
- Multiple sclerosis
- Myasthenia gravis
- Idiopathic inflammatory myopathy
- Parkinson’s disease
This area includes both relapsing and progressive neurological conditions, as well as pediatric neuroinflammatory disease.
Oncology and Hematologic Malignancies
Trial involvement covers a broad oncology landscape, with emphasis on solid tumors and blood cancers that require targeted or immune-based treatment strategies.
- Breast cancer
- Lung cancer
- Renal cell carcinoma
- Lymphoma
Related interests include multiple myeloma, urothelial carcinoma, ovarian cancer, and other advanced malignancies.
Cardiometabolic and Hepatic Disease
The investigator’s research landscape includes chronic cardiovascular and metabolic disorders, alongside liver disease and related complications that require long-term medical management.
- Atherosclerotic cardiovascular disease
- Heart failure
- Chronic liver disease
- Non-alcoholic steatohepatitis
Additional therapeutic focus includes stroke prevention, obesity, and diabetes mellitus.
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