María Isabel G. R.
- Country
- Spain
- Department
- Urology
Research Overview
Data & Insights
Has run more than one trial at 0 of 33 partner sites.
Specializations
Urothelial and Bladder Cancer
Focuses on malignant diseases of the urinary tract, particularly urothelial carcinoma and bladder cancer, addressing both non‑muscle invasive and muscle‑invasive forms.
- High‑risk non‑muscle invasive bladder cancer
- Muscle‑invasive urothelial carcinoma
- Adjuvant therapy after transurethral resection
- Immunotherapy combinations for advanced disease
Clinical activity includes evaluation of novel agents within the Hospital Clinico San Carlos setting.
Renal Cell Carcinoma and Kidney Disorders
Addresses malignant and non‑malignant renal conditions, including clear cell renal cell carcinoma, non‑clear cell renal cell carcinoma, and chronic kidney disease associated with diabetes.
- Targeted therapy for clear cell RCC
- First‑line options for non‑clear cell RCC
- Renal impairment management in diabetic patients
- Study of IgA nephropathy therapies
Research integrates molecular profiling to guide personalized treatment strategies.
Prostate Cancer
Specializes in advanced prostate malignancies, notably metastatic castration‑resistant prostate cancer and high‑risk localized disease.
- Hormone‑refractory prostate cancer
- Combination androgen deprivation therapy with novel agents
- Biomarker‑driven treatment selection
- Radioligand therapy for bone metastases
Efforts aim to improve survival and quality of life for patients with aggressive disease phenotypes.
Cardiovascular and Thrombotic Conditions
Extends expertise to cardiovascular disorders, covering atherosclerotic cardiovascular disease, atrial fibrillation, and acute coronary events.
- Secondary prevention after myocardial infarction
- Antithrombotic strategies post‑PCI
- Lipoprotein(a)‑targeted therapies
- Management of heart failure with preserved ejection fraction
Investigations incorporate risk stratification and emerging lipid‑lowering modalities.
Immunology and Rare Renal/Autoimmune Diseases
Investigates immune‑mediated renal and systemic diseases such as IgA nephropathy, complement‑mediated glomerulopathies, and systemic lupus erythematosus.
- Complement inhibition in membranoproliferative glomerulonephritis
- Targeted therapy for C3 glomerulopathy
- Autoimmune hemolytic anemia treatment strategies
- Novel biologics for systemic lupus erythematosus
Research focuses on translating immunologic insights into therapeutic advances.
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