María Inmaculada S. M.
- Country
- Spain
- Department
- Allergy
Research Overview
Data & Insights
Has run more than one trial at 0 of 1 partner site.
Specializations
Allergy & Respiratory Immunology
Focused on the pathophysiology and treatment of allergic rhinitis and eosinophilic asthma, with particular attention to sensitization by Dermatophagoides species.
- Allergic rhinitis to Dermatophagoides pteronyssinus and farinae
- Severe eosinophilic asthma management
- Allergen immunotherapy strategies
Clinical investigations aim to improve symptom control and reduce reliance on systemic corticosteroids.
Autoimmune & Rheumatology
Engaged in studies of systemic autoimmune diseases such as rheumatoid arthritis, psoriatic arthritis, systemic lupus erythematosus, and Sjögren’s syndrome.
- Rheumatoid arthritis therapeutic optimization
- Psoriatic arthritis stratified by prior biologic exposure
- Sjögren’s syndrome with moderate‑to‑severe systemic activity
- Systemic lupus erythematosus renal involvement
Research emphasizes disease‑modifying agents and patient‑centered outcomes.
Hematologic & Oncology Therapeutics
Broad oncology portfolio covering solid tumors and hematologic malignancies, including breast cancer subtypes, soft‑tissue sarcoma, acute myeloid leukemia, and multiple myeloma.
- Hormone‑receptor positive, HER2‑negative breast cancer targeted therapy
- Soft‑tissue sarcoma treatment sequencing
- Acute myeloid leukemia novel agents
- Multiple myeloma relapse prevention
- HER2‑positive breast cancer antibody‑drug conjugates
Efforts aim to enhance survival and address resistance mechanisms.
Infectious & Transplant Immunology
Investigations into viral infections, bacterial endocarditis, and transplant‑related immune modulation, notably human immunodeficiency virus and renal transplantation.
- HIV antiretroviral optimization
- Enterococcus faecalis infective endocarditis
- Kidney transplantation immunosuppression strategies
- Metabolic syndrome management in transplant candidates
Studies target long‑term graft function and infection control.
Cardiovascular & Metabolic Disease
Research addressing atherosclerotic risk, obesity, and related metabolic disorders, with a focus on primary prevention and therapeutic innovation.
- Atherosclerotic cardiovascular disease primary prevention
- Obesity intervention trials
- Type 2 diabetes metabolic control
- Statin‑related genotyping safety
Objectives include reducing major adverse cardiovascular events and improving metabolic health.
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