Maria del Mar R. B.
- Country
- Spain
- Department
- Hepatology
Research Overview
Data & Insights
Has run more than one trial at 0 of 36 partner sites.
Specializations
Liver Cancer Therapeutics
Focus on advanced hepatocellular carcinoma and related solid tumor interventions.
- Immunotherapy in HCC
- Targeted kinase inhibitors
- Combination regimens with anti‑PD‑L1 agents
Clinical investigations emphasize biomarker‑driven patient selection.
Acute‑on‑Chronic Liver Failure
Studies address pathophysiology and treatment of ACLF in cirrhotic patients.
- Systemic inflammation modulation
- Renal support strategies
- Novel albumin‑based therapies
Multi‑center enrollment at Hospital Vall d’Hebron supports real‑world outcomes.
Metabolic Liver Disease
Research on progressive non‑alcoholic steatohepatitis (NASH) and related metabolic dysfunction.
- Fibrosis regression agents
- FXR agonists
- Combination metabolic‑cardiovascular trials
Integrates imaging biomarkers and liver biopsy endpoints.
Biliary Tract Oncology
Investigations target intrahepatic and extrahepatic cholangiocarcinoma and gallbladder malignancies.
- IDH1‑mutated cholangiocarcinoma therapies
- FGFR2‑fusion inhibitors
- Adjuvant chemoradiation protocols
Emphasis on molecular stratification and surgical outcomes.
Liver Transplantation & Immune Disorders
Clinical work includes post‑transplant graft function and autoimmune liver conditions such as primary biliary cholangitis.
- Immunosuppression optimization
- Graft‑versus‑host disease prevention
- Autoimmune hepatitis biologics
Collaborative network enhances long‑term graft survival studies.
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