Maria-Cristina B.
- Country
- Belgium
- Department
- Department of Endocrinology and Nutrition
Research Overview
- Phase 3 Randomized Double‑Masked Placebo‑Controlled Study of Subcutaneous Efgartigimod Alfa in Adults with Graves’ Disease Inadequately Controlled by Antithyroid Drugs
- Evaluation of Batoclimab Efficacy and Safety in an Open-Label Extension Study for Thyroid Eye Disease Treatment in Participants Completing IMVT-1401-3201/3202
- Phase 3 Randomized Quadruple-Masked Placebo-Controlled Trial of Batoclimab in Active Thyroid Eye Disease
Data & Insights
Has run more than one trial at 23 of 109 partner sites.
Specializations
Inflammatory Bowel Disease and Gastroenterology
Maria-Cristina Burlacu is involved in clinical research on ulcerative colitis and Crohn’s disease, with interest in both adult and pediatric disease management. Her work also extends to broader inflammatory bowel diseases and related gastrointestinal inflammatory conditions.
- Moderately to severely active ulcerative colitis
- Moderately to severely active Crohn’s disease
- Inflammatory bowel diseases
- Gastrointestinal inflammation
Her trial portfolio reflects a focus on improving control of chronic intestinal inflammation and supporting advances in targeted and biologic therapies.
Autoimmune and Dermatologic Disorders
Her research interests include immune-mediated skin and systemic diseases such as psoriasis, hidradenitis suppurativa, prurigo nodularis, and cutaneous lupus erythematosus. She is also connected to studies in rheumatoid arthritis and systemic lupus erythematosus.
- Moderate to severe plaque psoriasis
- Hidradenitis suppurativa
- Prurigo nodularis
- Cutaneous lupus erythematosus
This area highlights a therapeutic emphasis on chronic inflammatory disease control and symptom relief in immune-driven conditions.
Hematology and Cellular Therapy
She contributes to clinical studies in acute lymphoblastic leukemia, myeloma, lymphoma, and other hematologic malignancies. Her portfolio includes research linked to allogeneic hematopoietic stem cell transplantation and advanced immune-based treatment strategies.
- Acute lymphoblastic leukemia
- Multiple myeloma
- Non-Hodgkin lymphoma
- Hematopoietic stem cell transplantation
Her involvement spans malignancies requiring intensive hematologic care and innovative treatment approaches in blood cancers.
Oncology and Solid Tumors
Her clinical research landscape includes multiple solid tumors, especially breast cancer, colorectal cancer, lung cancer, ovarian cancer, endometrial cancer, and head and neck cancer. She is also associated with studies in melanoma, urothelial carcinoma, and pancreatic cancer.
- Breast cancer
- Colorectal cancer
- Non-small cell lung cancer
- Gynecologic malignancies
This profile shows broad engagement with precision oncology and therapeutic development across advanced malignancies.
Kidney, Liver, and Cardiometabolic Disease
Maria-Cristina Burlacu is also linked to trials in chronic kidney disease, proteinuric kidney disease, IgA nephropathy, and polycystic kidney disease. Additional interests include liver disease, cholestatic disorders, atherosclerotic cardiovascular disease, heart failure, diabetes mellitus, and obesity.
- Chronic kidney disease
- Proteinuric kidney disorders
- Liver and cholestatic disease
- Cardiometabolic disease
Her research activity in these domains reflects interest in complex multisystem disease management and emerging targeted therapies.
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