Maria Chiara Z.
- Country
- Italy
- Department
- NA
Research Overview
- Efficacy and Safety of Zenagamtide in Participants with Obesity: A Randomized Controlled Trial to Evaluate Weight Maintenance
- Efficacy and Safety Evaluation of Debio 4126, a 12-Week Octreotide Formulation, in Acromegaly Patients Previously Treated with Somatostatin Analogs
- Efficacy and Safety Evaluation of ALXN2420 with Somatostatin Analogs in Adult Acromegaly: A Phase 2 Randomized, Double-Blind, Placebo-Controlled Study
Data & Insights
Has run more than one trial at 16 of 101 partner sites.
Specializations
Cardiovascular medicine and metabolic risk
Maria Chiara Zatelli is involved in clinical research on atherosclerotic cardiovascular disease, acute myocardial infarction, atrial fibrillation, and heart failure, with additional interest in hypertension, obesity, and hypertriglyceridemia.
- Myocardial infarction and coronary event prevention
- Atrial fibrillation and stroke prevention
- Heart failure and cardiorenal disease
- Lipid disorders and cardiometabolic risk
The therapeutic landscape also includes calcific aortic valve stenosis, transthyretin amyloid cardiomyopathy, and other cardiovascular conditions linked to inflammation and residual vascular risk.
Hematology and blood cancers
Her research activity covers a broad spectrum of hematologic malignancies, including chronic lymphocytic leukemia, acute myeloid leukemia, chronic myeloid leukemia, myelodysplastic syndromes, and myelofibrosis.
- Chronic lymphocytic leukemia and small lymphocytic lymphoma
- Acute myeloid leukemia and FLT3-mutated disease
- Myelodysplastic syndromes and myeloproliferative neoplasms
- Lymphoma and Richter transformation
Her therapeutic focus extends to targeted therapy, BCL-2 inhibition, BTK inhibition, and treatment strategies for relapsed or high-risk disease.
Autoimmune and inflammatory disorders
She is active in studies of systemic lupus erythematosus, lupus nephritis, systemic sclerosis, psoriatic arthritis, and giant cell arteritis, along with other immune-mediated conditions.
- Systemic lupus erythematosus and lupus nephritis
- Systemic sclerosis and connective tissue disease
- Psoriatic arthritis and hidradenitis suppurativa
- Giant cell arteritis and immune dysregulation
This area includes interest in immunomodulatory therapy and inflammatory disease control across multisystem autoimmune conditions.
Respiratory and allergic disease
Her clinical trial portfolio includes asthma, chronic obstructive pulmonary disease, bronchiectasis, and chronic rhinosinusitis with nasal polyps, reflecting a strong focus on chronic airway disease.
- Severe asthma and eosinophilic airway inflammation
- COPD with frequent exacerbations
- Bronchiectasis and chronic respiratory infection
- Upper and lower airway inflammatory disease
Her research also touches on respiratory tract disease and treatment options aimed at reducing exacerbations and persistent inflammation.
Oncology and solid tumors
Maria Chiara Zatelli is involved in clinical research across several solid tumors, including breast cancer, non-small cell lung cancer, prostate cancer, ovarian cancer, melanoma, and hepatocellular carcinoma.
- Breast cancer and hormone receptor–driven disease
- Non-small cell lung cancer and thoracic oncology
- Prostate cancer and metastatic castration-resistant disease
- Ovarian cancer, melanoma, and hepatobiliary cancer
Her therapeutic interests include precision oncology, endocrine-based treatment, and immunotherapy across advanced and recurrent malignancies.
Related Investigators
Researchers in similar fields or departments
Want to know more about this investigator?
We can share extended profile information and contact details.
Is something out of date?
Tell us what needs correcting and we'll update this profile.