Maria Aranzazu J. B.
- Country
- Spain
- Department
- Allergy
Research Overview
Data & Insights
Has run more than one trial at 0 of 35 partner sites.
Specializations
Allergic Respiratory Disorders
The investigator explores therapeutic approaches for allergic rhinitis. Additional focus includes allergic rhinoconjunctivitis. Studies also address co‑existing asthma.
- Polymerized allergen immunotherapy
- Grass and olive pollen AIT
- Symptom and medication score assessment
Emphasis is placed on seasonal pollen exposure and ARIA classification criteria.
Chronic Spontaneous Urticaria
Research targets disease mechanisms underlying chronic spontaneous urticaria. The aim is to reduce symptom severity in patients with moderate to severe disease.
- Efficacy of novel oral agents
- Dose‑ranging studies
- Patient‑reported outcome measures
Therapeutic strategies are evaluated for rapid control of wheals and pruritus.
Non‑Small Cell Lung Cancer (NSCLC)
Clinical work concentrates on tumours expressing c-Met. Parallel investigations involve cancers that are EGFR wildtype. The focus is on advanced and metastatic disease stages.
- c-Met directed antibody‑drug conjugates
- Comparative efficacy versus standard chemotherapy
- Biomarker‑driven patient selection
Efforts aim to improve progression‑free and overall survival outcomes.
HER2‑Positive Breast Cancer
Therapeutic development targets tumours classified as HER2‑positive. Studies address non‑resectable or metastatic disease contexts.
- Trastuzumab with tucatinib and vinorelbine
- Synergistic targeted therapy
- Resistance mitigation strategies
Combination regimens are evaluated for enhanced survival benefits.
Infectious and Gastrointestinal Oncology
Vaccine research includes the immunogenicity of Respiratory Syncytial Virus formulations in older adults. Parallel oncology work examines adjuvant approaches for colorectal cancer.
- RSV vaccine immunogenicity
- ctDNA‑guided adjuvant therapy
- Disease‑free survival endpoints
The dual focus integrates virology insights with colorectal cancer management.
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