Maria Angeles A. Z.
- Country
- Spain
- Department
- Rheumatology
Research Overview
Data & Insights
Has run more than one trial at 0 of 11 partner sites.
Specializations
Systemic Autoimmune Rheumatic Diseases
The investigator’s work centers on systemic autoimmune rheumatic conditions that affect multiple organ systems. Research seeks to improve disease control and reduce long‑term organ damage.
- Systemic lupus erythematosus
- Rheumatoid arthritis
- Psoriatic arthritis
- Systemic sclerosis
- Idiopathic inflammatory myopathy
These efforts integrate clinical expertise with emerging therapeutic strategies.
Cutaneous Autoimmune Disorders
A major focus is on skin‑limited autoimmune diseases that present diagnostic and therapeutic challenges. The studies explore pathways linking skin inflammation with systemic autoimmunity.
- Cutaneous lupus erythematosus
- Subacute cutaneous lupus erythematosus
- Discoid lupus erythematosus
- Atopic dermatitis
- Prurigo nodularis
Targeted therapies aim to reduce skin lesions while preserving systemic health.
Cardiovascular and Lipoprotein Abnormalities
The investigator addresses cardiovascular disease risk associated with inflammatory and lipid disorders. Understanding these links supports integrated management of patients with high cardiovascular burden.
- Atherosclerotic cardiovascular disease
- Elevated lipoprotein(a)
- Hypertension
- Hypercholesterolemia
- Peripheral arterial disease
Research evaluates both traditional and novel risk‑modifying interventions.
Renal Immunopathology
Renal involvement in autoimmune disease is a therapeutic priority for preserving kidney function. Studies investigate immune‑mediated renal injury and strategies to prevent transplant rejection.
- Lupus nephritis
- IgA nephropathy
- Focal segmental glomerulosclerosis
- Chronic kidney disease
- Kidney transplant rejection prevention
These projects aim to balance immune suppression with renal preservation.
Immune‑Mediated Hematologic and Oncologic Conditions
Beyond classic rheumatology, the investigator contributes to immune‑driven malignancy studies. The goal is to define how immune modulation influences cancer outcomes.
- Multiple myeloma
- Chronic lymphocytic leukemia
- Non‑small cell lung cancer with immune checkpoint targets
- Metastatic breast cancer
- Autoimmune hemolytic anemia
Collaborative trials explore combinations of immunotherapy and disease‑specific agents.
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