Margreet K.
- Country
- The Netherlands
- Department
- Rheumatology
Research Overview
Data & Insights
Has run more than one trial at 0 of 3 partner sites.
Specializations
Autoimmune Neuromuscular Disorders
Focused on antibody‑mediated muscle weakness and related neuromuscular conditions.
- Myasthenia Gravis
- Generalized Myasthenia Gravis
- Ocular Myasthenia Gravis
- Acetylcholine Receptor Antibody Positive MG
- Acetylcholine Receptor Antibody Negative MG
Clinical investigations address disease activity, therapeutic response, and long‑term outcomes.
Systemic Connective Tissue Diseases
Research on multisystem autoimmune diseases affecting skin, vasculature, and internal organs.
- Systemic lupus erythematosus
- Lupus nephritis
- Systemic sclerosis
- Diffuse cutaneous systemic sclerosis
- ANCA‑associated vasculitis
- C3 glomerulopathy
Emphasis on biomarkers and novel immunomodulatory strategies.
Inflammatory Joint Diseases
Studies targeting chronic arthritis and related joint pathology.
- Rheumatoid arthritis
- Moderately active rheumatoid arthritis
- Hand osteoarthritis
- Psoriatic arthritis
Trials evaluate disease‑modifying antirheumatic drugs and patient‑reported outcomes.
Rare Metabolic & Genetic Disorders
Investigation of hereditary conditions with systemic impact.
- Alpha‑1 antitrypsin deficiency
- Autosomal dominant polycystic kidney disease
- Osteogenesis imperfecta
- Duchenne muscular dystrophy
Focus on disease progression, organ‑specific complications, and emerging gene‑based therapies.
Oncology & Hematologic Malignancies
Participation in trials for hematologic and solid tumors with immunologic relevance.
- Diffuse large B‑cell lymphoma
- Chronic lymphocytic leukemia
- Multiple myeloma
- Non‑small cell lung cancer
- Breast cancer
Investigations often involve immune‑targeted agents and combination regimens.
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