Mareike A.
- Country
- Germany
- Department
- 9196: Klinik fuer Dermatologie HautTumorCentrum
Research Overview
- A Phase 2a, Randomized, Double-blind, Placebo-controlled Study to Evaluate the Efficacy and Safety of NAV-240 in Adults with Moderate-to-Severe Hidradenitis Suppurativa
- Phase 3 Extension Study of Long-Term Safety and Efficacy of Remibrutinib in Adults With Moderate to Severe Hidradenitis Suppurativa
- Phase 3 Evaluation of Remibrutinib Efficacy and Safety in Adults with Moderate to Severe Hidradenitis Suppurativa
Data & Insights
Has run more than one trial at 56 of 120 partner sites.
Specializations
Dermatology and inflammatory skin disease
The investigator is involved in clinical research on hidradenitis suppurativa, advanced basal cell carcinoma, and Merkel cell carcinoma, with additional interest in melanoma and other cutaneous malignancies.
- Moderate-to-severe hidradenitis suppurativa
- Basal cell carcinoma
- Merkel cell carcinoma
- Melanoma
Clinical activity in this area reflects a focus on immune-mediated skin disorders and skin cancer treatment strategies within dermatology.
Melanoma and skin cancer immunotherapy
Research involvement includes treatment development for advanced melanoma, resected melanoma, and NRAS-mutant cutaneous melanoma, as well as broader studies in skin cancer immunotherapy.
- Advanced melanoma
- High-risk resected melanoma
- NRAS mutant cutaneous melanoma
- Skin cancer immunotherapy
The therapeutic emphasis extends to immune checkpoint-based approaches and combination strategies in advanced cutaneous oncology.
Hematologic malignancies
The investigator participates in studies across a broad spectrum of blood cancers, including acute myeloid leukemia, acute lymphoblastic leukemia, diffuse large B-cell lymphoma, mantle cell lymphoma, multiple myeloma, and myeloproliferative neoplasms.
- Acute myeloid leukemia
- Acute lymphoblastic leukemia
- Diffuse large B-cell lymphoma
- Myelofibrosis and essential thrombocythemia
These activities cover both adult and pediatric hematology, with interest in targeted therapy, immunotherapy, and treatment innovation in aggressive hematologic disease.
Thoracic and gastrointestinal oncology
Clinical trial involvement also spans non-small cell lung cancer, small cell lung cancer, and gastroesophageal adenocarcinoma, including locally advanced, metastatic, and resectable disease settings.
- Non-small cell lung cancer
- Small cell lung cancer
- Gastroesophageal adenocarcinoma
- Metastatic colorectal cancer
The therapeutic focus includes systemic treatment combinations and perioperative approaches for solid tumors with high unmet need.
Autoimmune and acute vascular disease
Additional research interests include systemic sclerosis-associated interstitial lung disease, connective tissue disease-associated interstitial lung disease, chemotherapy-induced polyneuropathy, and acute ischemic stroke.
- Systemic sclerosis-associated interstitial lung disease
- Connective tissue disease-associated interstitial lung disease
- Chemotherapy-induced polyneuropathy
- Acute ischemic stroke
This profile also includes therapeutic work in inflammatory lung disease and neurologic emergency care.
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