Marcus P.
- Country
- Sweden
- Department
- VO Vuxenpsykiatri Helsingborg
Research Overview
- Efficacy and Safety of Psilocybin (COMP360) in Adults with Treatment-Resistant Depression: A Phase III Randomized, Double-Blind, Controlled Trial
- Evaluation of Accelerated Intermittent Theta-Burst Stimulation with D-Cycloserine Augmentation in Major Depressive Disorder: A Randomized, Double-Blind, Placebo-Controlled Trial
Data & Insights
Has run more than one trial at 2 of 39 partner sites.
Specializations
Cardiovascular Therapeutics
Focuses on interventions for acute myocardial infarction, atherosclerotic cardiovascular disease, and heart failure with renal involvement.
- balcinrenone/dapagliflozin in heart failure
- asundexian versus apixaban for stroke prevention
- olpasiran targeting elevated lipoprotein(a)
- selatogrel self‑administration for recurrent infarction
- vasopressor therapy in hypotensive shock
Investigations aim to reduce cardiovascular mortality and hospitalizations.
Infectious Disease Therapeutics
Explores treatments for multidrug‑resistant bacterial infections and severe viral lung disease.
- alternative oral regimens for ESBL‑producing urinary infections
- early vasopressor use in septic shock
- novel monoclonal antibodies against Clostridioides difficile
- tozorakimab as adjunct in viral pneumonia
- optimized antibiotics for Staphylococcus aureus bacteremia
Emphasis on safety and rapid pathogen clearance.
Hematologic Oncology
Dedicated to novel regimens for relapsed or refractory plasma cell malignancies.
- teclistamab combinations for multiple myeloma
- etentamig monotherapy in heavily pretreated disease
- iberdomide with daratumumab
- BCMA‑CD3 bispecific antibodies for durable remission
- elranatamab versus lenalidomide post‑transplant
Goals include deeper responses and prolonged progression‑free survival.
Psychiatric and Neurologic Therapeutics
Targets refractory mood disorders and psychotic conditions using pharmacologic and neuromodulatory approaches.
- COMP360 for treatment‑resistant depression
- NBI‑1065845 adjunctive therapy in major depressive disorder
- rituximab immunomodulation in schizophrenia spectrum
- cortisol treatment for facial nerve palsy
- brain stimulation techniques for depressive symptoms
Research seeks durable symptom improvement and functional recovery.
Neurostimulation and Device‑Based Therapies
Investigates cerebral stimulation modalities to modulate neural circuits in neuropsychiatric disease.
- transcranial magnetic stimulation for depression
- deep brain stimulation in treatment‑resistant schizophrenia
- non‑invasive vagus nerve stimulation for mood regulation
- closed‑loop neurofeedback for cognitive enhancement
- brain‑computer interfaces for motor recovery
Integrates electrophysiological monitoring with therapeutic delivery.
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