Marco L.
- Country
- Italy
- Department
- Medicina sperimentale e clinica, clinica oculistica
Research Overview
- Evaluation of Ranibizumab Port Delivery System Refill Regimens in Neovascular Age-Related Macular Degeneration: A Phase IIIb Randomized Study
- Evaluation of Intravitreal BI 764524 in Moderately-Severe to Severe Non-Proliferative Diabetic Retinopathy: A Randomized, Sham-Controlled, Double-Masked Trial
- Evaluation of Long-Term Safety and Tolerability of Ranibizumab via Port Delivery System in Neovascular Age-Related Macular Degeneration Patients
Data & Insights
Has run more than one trial at 95 of 199 partner sites.
Specializations
Ophthalmology and retinal disease
Clinical research activity includes therapeutic interest in age-related macular degeneration, diabetic retinopathy, macular edema, and retinal vein occlusion, with attention to visual outcomes and chronic retinal vascular disease.
- Neovascular age-related macular degeneration
- Atrophic age-related macular degeneration
- Diabetic retinopathy
- Macular edema
Work in this area is aligned with the management of degenerative and vascular eye disorders in a specialist ophthalmology setting.
Haematology and blood cancers
The investigator is extensively involved in trials for acute myeloid leukemia, acute lymphoblastic leukemia, multiple myeloma, and myelodysplastic syndromes, with strong interest in disease control, minimal residual disease, and relapse prevention.
- Acute myeloid leukemia
- Acute lymphoblastic leukemia
- Multiple myeloma
- Myelodysplastic syndromes
Additional activity covers lymphoma, hairy cell leukemia, and plasma cell dyscrasias, reflecting a broad therapeutic focus in malignant hematology.
Solid tumours and precision oncology
Research interests include advanced and metastatic breast cancer, non-small cell lung cancer, colorectal cancer, ovarian cancer, gastric cancer, and head and neck squamous cell carcinoma, with emphasis on biomarker-driven treatment selection.
- Breast cancer
- Non-small cell lung cancer
- Colorectal cancer
- Urothelial carcinoma
The portfolio also includes melanoma, pancreatic cancer, and hepatocellular carcinoma, supporting a wide oncology profile in targeted and immunotherapy-based care.
Inflammatory, autoimmune, and dermatologic disease
Clinical activity spans psoriatic arthritis, atopic dermatitis, psoriasis, hidradenitis suppurativa, systemic lupus erythematosus, and systemic sclerosis, with interest in immune-mediated skin and joint disorders.
- Psoriatic arthritis
- Atopic dermatitis
- Chronic plaque psoriasis
- Systemic lupus erythematosus
Related involvement extends to Sjögren’s syndrome, rheumatoid arthritis, and juvenile idiopathic arthritis, indicating a sustained therapeutic interest in chronic inflammatory disease.
Pulmonology, rare disease, and cardiovascular medicine
The research landscape also includes idiopathic pulmonary fibrosis, progressive fibrosing interstitial lung disease, asthma, and cystic fibrosis, alongside cardiovascular and thromboembolic conditions such as atrial fibrillation, heart failure, and pulmonary embolism.
- Idiopathic pulmonary fibrosis
- Progressive fibrosing interstitial lung disease
- Atrial fibrillation
- Heart failure
Additional therapeutic interest is seen in neurodevelopmental injury, diabetes mellitus, and amyloidosis, broadening the clinical scope beyond oncology and immune disease.
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