Marcio D.
- Country
- Portugal
- Department
- Breast Unit
Research Overview
- A Phase III, Randomized, Double-blind Study to Evaluate Pembrolizumab plus Chemotherapy vs Placebo plus Chemotherapy as Neoadjuvant Therapy and Pembrolizumab vs Placebo as Adjuvant Therapy for Triple Negative Breast Cancer (TNBC)
- Evaluation of Trastuzumab Deruxtecan in Unresectable/Metastatic HER2-low or HER2 IHC0 Breast Cancer: A Multicenter, Open-label Study
- Phase 3 Randomized Study of Pembrolizumab Plus Chemotherapy Versus Placebo Plus Chemotherapy in HR+/HER2- Metastatic Breast Cancer
Data & Insights
Has run more than one trial at 101 of 329 partner sites.
Specializations
Advanced Breast Cancer Treatment
This investigator specializes in treating various forms of advanced breast cancer, with particular emphasis on triple negative breast cancer (TNBC) and hormone receptor-positive (HR+) breast cancer.
- Neoadjuvant and adjuvant therapy approaches
- Locally advanced breast cancer management
- Metastatic disease treatment strategies
Their work encompasses both early-stage and advanced disease states, focusing on innovative therapeutic combinations.
Targeted Therapies
The investigator focuses on novel targeted treatments including CDK4/6 inhibitors and HER2-directed therapies. Their expertise extends to treating patients with specific molecular profiles, including those with ESR1 mutations.
- HER2-low breast cancer treatment
- Hormone receptor targeting
- Molecular-based therapy selection
Their research incorporates biomarker-driven treatment approaches for personalized cancer care.
Immunotherapy Applications
The investigator explores immunotherapy combinations in breast cancer treatment, particularly focusing on PD-L1 expression and its role in treatment selection.
- Immunotherapy-chemotherapy combinations
- PD-L1 biomarker assessment
- Novel immunotherapy approaches
Their work evaluates innovative immunotherapeutic strategies across different breast cancer subtypes.
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