Marcin G.
- Country
- Poland
- Department
- N/A
Research Overview
- A Multicenter, Open-Label, Dose Escalation Study to Evaluate the Safety, Tolerability, and Efficacy of Budiodarone in Subjects with Non-permanent Atrial Fibrillation
- Efficacy and Safety of LY3540378 in Adults with Worsening Chronic Heart Failure with Preserved Ejection Fraction: A Phase 2 Randomized, Double-Blind, Placebo-Controlled Study
- Efficacy of Evolocumab Versus Standard Care in LDL-C Reduction for Acute Myocardial Infarction Patients Undergoing Percutaneous Coronary Intervention
Data & Insights
Has run more than one trial at 55 of 315 partner sites.
Specializations
Cardiovascular Medicine
Clinical activity includes acute myocardial infarction, atrial fibrillation, heart failure, atherosclerotic cardiovascular disease, and myocardial injury after noncardiac surgery, with additional involvement in hypertension and critical limb ischemia.
- Acute coronary syndromes
- Heart failure with reduced ejection fraction and heart failure with preserved ejection fraction
- Anticoagulation in atrial fibrillation
- Inflammatory cardiomyopathy and myocarditis
Work in this area also extends to cardiac amyloidosis, hypertrophic cardiomyopathy, and recurrent pericarditis.
Hematology and Oncology
Research interests cover acute myeloid leukemia, acute lymphoblastic leukemia, chronic lymphocytic leukemia, multiple myeloma, and lymphoma, together with broader work in myelodysplastic syndrome and plasma cell dyscrasia.
- Relapsed and refractory B-cell malignancies
- Maintenance therapy after transplantation
- High-risk myeloid neoplasms
- Targeted immunotherapy in blood cancers
Additional involvement includes pediatric leukemia, follicular lymphoma, marginal zone lymphoma, and light chain amyloidosis.
Autoimmune and Neuromuscular Disorders
Therapeutic focus includes myasthenia gravis, multiple sclerosis, myelin oligodendrocyte glycoprotein antibody-associated disease, multifocal motor neuropathy, and chronic inflammatory demyelinating polyradiculoneuropathy.
- Generalized myasthenia gravis
- Relapsing multiple sclerosis
- Autoantibody-mediated neurologic disease
- Peripheral nerve immune disorders
Research also includes spinal muscular atrophy and Duchenne muscular dystrophy, reflecting activity across autoimmune and inherited neuromuscular conditions.
Renal and Complement-Mediated Disease
Clinical trial involvement spans chronic kidney disease, IgA nephropathy, idiopathic immune complex mediated membranoproliferative glomerulonephritis, atypical hemolytic uremic syndrome, and delayed graft function after kidney transplantation.
- Proteinuric glomerular disease
- Complement-mediated nephropathies
- Kidney transplant complications
- Hypertension-associated renal disease
Additional interest includes lupus nephritis, childhood nephrotic syndrome, and multiple autoimmune glomerular diseases.
Rare Disease and Immunology
Activity also covers systemic lupus erythematosus, subacute cutaneous lupus erythematosus, chronic cutaneous lupus erythematosus, thyroid eye disease, and pulmonary sarcoidosis.
- Fibrosing interstitial lung disease
- Heritable thoracic aortic disease
- Hemophilia and other bleeding disorders
- Gout with hyperuricemia
Further involvement includes Marfan syndrome, progressive fibrosing pulmonary disease, and non-infectious uveitis.
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