person

Marc T.

Country
France
Department
N/A

Research Overview

Data & Insights

medical_services
Primary Speciality
Main therapeutic area

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Return Partnerships
Recurring site collaborations
0
Sites with multiple studies

Has run more than one trial at 0 of 40 partner sites.

Specializations

Hematologic Malignancies

The investigator focuses on malignant disorders of the blood and bone marrow, addressing both lymphoid and myeloid lineages.

  • Treatment of Acute Myeloid Leukemia and related high‑risk myelodysplastic syndromes
  • Therapeutic strategies for Chronic Lymphocytic Leukemia and small lymphocytic lymphoma
  • Management of Multiple Myeloma in relapsed or refractory settings
  • Targeted approaches for Diffuse Large B‑Cell Lymphoma and other aggressive B‑cell lymphomas
  • Allogeneic stem cell transplantation for high‑risk hematologic cancers

Research integrates novel agents, immunotherapies, and transplant modalities to improve survival in these diseases.

Solid Tumor Oncology

Extensive work is conducted on a broad spectrum of solid cancers, emphasizing advanced and metastatic disease.

  • Clinical investigation of Non‑Small Cell Lung Cancer, including ALK‑positive and EGFR‑mutated subtypes
  • Therapeutic development for Breast Cancer, especially triple‑negative and HER2‑positive forms
  • Targeted treatment of Colorectal Cancer with KRAS/NRAS/BRAF wild‑type and mutated profiles
  • Management of Urothelial Carcinoma and metastatic bladder cancer
  • Innovative approaches for Melanoma and other cutaneous malignancies

Efforts combine molecularly guided therapies, immuno‑oncology, and combination regimens.

Autoimmune and Inflammatory Diseases

Investigation of immune‑mediated conditions spans systemic and organ‑specific disorders.

  • Therapeutic trials in Systemic Lupus Erythematosus and lupus nephritis
  • Management of ANCA‑associated Vasculitis and related pulmonary manifestations
  • Interventions for Atopic Dermatitis and severe eczema
  • Targeted treatment of Rheumatoid Arthritis and refractory disease
  • Novel agents for Inflammatory Bowel Disease including ulcerative colitis and Crohn’s disease

Focus lies on biologics, small‑molecule inhibitors, and personalized immunomodulation.

Infectious Diseases and Transplant Complications

Research addresses opportunistic infections and immune‑related complications in transplant recipients.

  • Management of Nontuberculous Mycobacterial Lung Infection caused by Mycobacterium avium complex
  • Prevention and treatment of CMV and HSV infections in immunocompromised patients
  • Therapeutic strategies for Graft‑Versus‑Host Disease, acute and chronic forms
  • Approaches to Invasive Fungal Infections including Aspergillus and Candida species
  • Optimization of outcomes after Allogeneic Hematopoietic Stem Cell Transplantation

Efforts aim to reduce infection‑related morbidity and improve post‑transplant immune regulation.

Cardiovascular and Metabolic Disorders

Clinical work encompasses acute cardiac events, chronic heart disease, and metabolic risk factors.

  • Intervention in Acute Coronary Syndrome, including STEMI and NSTEMI
  • Therapeutic evaluation for Heart Failure with preserved and reduced ejection fraction
  • Management of Atherosclerotic Cardiovascular Disease and elevated lipoprotein(a)
  • Treatment of Hypertension and associated renal complications
  • Metabolic control strategies for Type 2 Diabetes Mellitus

Research integrates pharmacologic and lifestyle interventions to mitigate cardiovascular risk.

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