Marc Alexander B.
- Country
- Germany
- Department
- Neuroradiologie
Research Overview
Data & Insights
Has run more than one trial at 0 of 15 partner sites.
Specializations
Pediatric Neuro‑Oncology Imaging
The work focuses on magnetic resonance imaging for diagnosis and monitoring of brain tumors in children.
- High‑grade glioma assessment
- Medulloblastoma response evaluation
- Low‑grade astrocytoma surveillance
- Imaging‑guided surgical planning
Integration of functional sequences supports treatment decision making.
Neurovascular Disorders in Children
Expertise includes cerebral angiography and advanced perfusion imaging for pediatric vascular pathologies.
- Arteriovenous malformation characterization
- Ischemic stroke imaging
- Venous sinus thrombosis evaluation
- Post‑intervention vessel patency
Imaging informs acute management and long‑term follow‑up.
Neuroinflammatory Disease Imaging
Application of quantitative MRI to visualize inflammatory activity in central nervous system disorders.
- Multiple sclerosis lesion mapping
- Neuro‑lupus cerebritis detection
- Autoimmune encephalitis monitoring
- Therapeutic response assessment
Provides objective biomarkers for disease activity.
Advanced Imaging of CNS Leukemia
Specialized diffusion‑weighted imaging techniques are employed to identify leukemic infiltration of the brain and spinal cord.
- Acute lymphoblastic leukemia CNS staging
- Acute myeloid leukemia meningeal involvement
- Therapeutic clearance evaluation
- Correlation with cerebrospinal fluid findings
Enhances diagnostic confidence in hematologic malignancies.
Imaging Biomarkers for Brain Development
Research utilizes structural and functional MRI to track neurodevelopmental trajectories in adolescents.
- Myelination pattern analysis
- Connectivity mapping in neurodevelopmental disorders
- Impact of early therapeutic interventions
- Longitudinal growth curve establishment
Supports precision medicine approaches for pediatric patients.
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