María del Mar C. R.
- Country
- Spain
- Department
- Neurology
Research Overview
- Efficacy and Safety of Intravenous Tenecteplase versus Standard of Care in Patients with Acute Ischemic Stroke Presenting >4.5 Hours from Last Known Well with Salvageable Tissue
- Colchicine for Reducing Dependency and MACE in Acute Intracerebral Hemorrhage Survivors with Atherosclerotic Risk: Randomized Placebo-Controlled Trial
- Phase 3 Randomized, Double-Blind, Placebo-Controlled Study of Asundexian for Ischemic Stroke Prevention in Adults Post-Acute Non-Cardioembolic Stroke or High-Risk TIA
Data & Insights
Has run more than one trial at 248 of 801 partner sites.
Specializations
Stroke and Neurovascular Care
Clinical research in acute ischemic stroke, high-risk transient ischemic attack, intracerebral haemorrhage, and endovascular treatment reflects a strong focus on urgent neurological care, reperfusion strategies, and prevention of early complications. The investigator is also involved in studies addressing mechanical thrombectomy, stroke recurrence, and anticoagulation-related decision-making in cerebrovascular disease.
- Acute ischemic stroke
- Intracerebral haemorrhage
- Mechanical thrombectomy
- Transient ischemic attack
Her work in this area links neurological intervention with secondary prevention and outcome optimisation in cerebrovascular disease.
Oncology and Solid Tumor Therapy
The investigator is active in a broad range of oncology studies, with particular involvement in breast cancer, non-small cell lung cancer, small cell lung cancer, ovarian cancer, endometrial cancer, and melanoma. Research interest extends to biomarker-defined and advanced malignancies, including HER2-positive, HR-positive, EGFR-mutated, and KRAS G12C-mutant tumors.
- Breast cancer
- Non-small cell lung cancer
- Ovarian cancer
- Melanoma
This portfolio includes interest in perioperative, metastatic, and biomarker-driven cancer treatment, with emphasis on therapeutic innovation in solid tumors.
Cardiovascular Medicine and Thromboembolic Disease
Her clinical trial activity includes heart failure, atrial fibrillation, atherosclerotic cardiovascular disease, myocardial infarction, hypertrophic cardiomyopathy, and cardiac amyloidosis. She is also involved in studies on stroke prevention, thromboembolism, and broader cardiovascular risk management, including lipid disorders and vascular inflammation.
- Heart failure
- Atrial fibrillation
- Cardiac amyloidosis
- Atherosclerotic cardiovascular disease
Her research profile also covers structural and genetic heart disease, together with prevention of major cardiovascular events.
Autoimmune, Inflammatory, and Rheumatologic Disorders
The investigator contributes to studies in systemic lupus erythematosus, cutaneous lupus erythematosus, psoriatic arthritis, rheumatoid arthritis, axial spondyloarthritis, and polymyalgia rheumatica. Additional interest is seen in Sjögren’s syndrome, systemic sclerosis, and dermatomyositis, reflecting a strong therapeutic focus on immune-mediated disease.
- Systemic lupus erythematosus
- Psoriatic arthritis
- Rheumatoid arthritis
- Systemic sclerosis
Her work spans chronic inflammatory syndromes with an emphasis on controlling immune activity and improving disease-specific outcomes.
Metabolic, Renal, and Hepatic Disease
Clinical interests also include type 2 diabetes mellitus, obesity, dyslipidemia, chronic kidney disease, IgA nephropathy, and kidney transplant rejection. In hepatology, the investigator is involved in non-alcoholic steatohepatitis and metabolic dysfunction-associated steatotic liver disease, alongside related cardiometabolic complications.
- Type 2 diabetes mellitus
- Chronic kidney disease
- Non-alcoholic steatohepatitis
- Obesity
This area reflects interest in interconnected metabolic and organ-specific disease pathways, including renal protection and liver disease modification.
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