Manuel R. G.
- Country
- Spain
- Department
- Unidad de ensayos clínicos aparato digestivo
Research Overview
- N1T-MC-MALO: A Master Protocol for a Randomized, Controlled, Clinical Trial of Multiple Pharmacologic Agents in Adult Participants With Metabolic Dysfunction-Associated Steatotic Liver Disease Who Are at Increased Risk of Developing Major Adverse Liver Outcomes (SYNERGY-Outcomes); N1T-MC-TZ01 Tirzepatide in participants with high-risk MASLD; N1T-MC-RT01 Retatrutide in participants with high-risk MASLD
- Phase 3 Randomized Double‑Blind Placebo‑Controlled Study of Efimosfermin Alfa Safety and Tolerability in Adults with F2‑F3 Metabolic Dysfunction‑Associated Steatohepatitis
- Phase 3 Randomized Double-Blind Placebo-Controlled Trial of Efruxifermin in Non-Cirrhotic NASH/MASH with Fibrosis
Data & Insights
Has run more than one trial at 170 of 349 partner sites.
Specializations
Liver Disease Management
This investigator specializes in treating various forms of liver conditions, with particular emphasis on non-alcoholic steatohepatitis (NASH) and liver fibrosis. Their research extends to both early-stage and advanced liver diseases.
- NASH with fibrosis stages F2/F3
- Metabolic dysfunction-associated steatotic liver disease
- Decompensated liver cirrhosis
Their work includes evaluation of novel therapeutic approaches for liver disease management and progression prevention.
Viral Hepatitis Treatment
The investigator focuses on developing treatments for chronic hepatitis B infection, exploring innovative therapeutic approaches including immunotherapy and antiviral treatments.
- Chronic HBV management
- Immunotherapy approaches
- Nucleos(t)ide analogue therapy
Their research encompasses both conventional antiviral treatments and emerging therapeutic strategies.
Liver Cancer Research
The investigator conducts research in hepatocellular carcinoma (HCC), focusing on advanced treatment methods for both intermediate and advanced-stage disease.
- Locally advanced HCC
- Metastatic liver cancer
- Combination immunotherapy approaches
Their work includes evaluation of novel therapeutic combinations and treatment strategies for various stages of liver cancer.
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