Manuel G. T.
- Country
- Spain
- Department
- 1503: Cirugía Plástica
Research Overview
- Efficacy and Safety of Alpelisib in Pediatric and Adult Patients with PIK3CA-Mutated Lymphatic Malformations: A Randomized, Double-Blind, Placebo-Controlled Study
- Phase 2 Evaluation of RLY-2608 in PIK3CA-Related Overgrowth Spectrum and PIK3CA Mutation-Driven Malformations in Adult and Pediatric Populations
- Phase II Evaluation of Alpelisib Efficacy, Safety, and Pharmacokinetics in Pediatric and Adult Patients with PIK3CA-Related Overgrowth Spectrum (PROS)
Data & Insights
Has run more than one trial at 19 of 53 partner sites.
Specializations
Breast Cancer and Gynecologic Oncology
Manuel Gómez Tellado is involved in clinical research across breast cancer, including HER2-positive, HER2-negative, hormone receptor-positive, triple-negative breast cancer, and early-stage breast cancer, as well as endometrial cancer, ovarian cancer, and cervical cancer.
- HER2-targeted therapy
- Endocrine-resistant breast cancer
- Platinum-resistant ovarian cancer
- Endometrial and cervical malignancies
His oncology portfolio also includes metastatic solid tumors and biomarker-driven treatment strategies in advanced disease.
Thoracic and Solid Tumor Oncology
His research activity extends to non-small cell lung cancer, small cell lung cancer, melanoma, gastric cancer, cholangiocarcinoma, and other advanced solid tumors.
- EGFR-mutated non-small cell lung cancer
- ALK-positive and ROS1-positive lung cancer
- Extensive-stage small cell lung cancer
- Metastatic melanoma
He is also engaged in studies involving targeted therapies and immuno-oncology for advanced malignancies.
Cardiovascular Medicine and Thrombosis
His clinical trial involvement includes heart failure, atrial fibrillation, atherosclerotic cardiovascular disease, myocardial infarction, stroke, and pulmonary embolism.
- Heart failure with preserved or reduced ejection fraction
- Ischemic stroke prevention
- Atrial fibrillation
- Cardiovascular risk reduction
He also contributes to research in transthyretin amyloid cardiomyopathy and hypertrophic cardiomyopathy.
Autoimmune, Inflammatory, and Rheumatologic Diseases
His therapeutic interests include rheumatoid arthritis, psoriatic arthritis, systemic lupus erythematosus, cutaneous lupus erythematosus, Sjögren’s syndrome, and systemic sclerosis.
- Axial spondyloarthritis
- Polymyalgia rheumatica
- Dermatomyositis
- Immune-mediated inflammatory disease
He is additionally involved in studies on immune thrombocytopenia and other autoimmune disorders.
Metabolic, Renal, and Neurologic Disorders
His research landscape also covers type 2 diabetes, obesity, non-alcoholic steatohepatitis, chronic kidney disease, IgA nephropathy, and kidney transplant rejection.
- Metabolic dysfunction-associated steatotic liver disease
- Diabetic peripheral neuropathic pain
- Parkinson’s disease
- Multiple sclerosis
He also participates in studies addressing neurodegenerative disease, pain management, and organ-specific complications.
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