Clinical Research
person

Manuel Fernandez B.

Country
Spain
Department
Oncology

Research Overview

assignment
1
Clinical Trials ·
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1
Research Sites

Data & Insights

medical_services
Primary Speciality
Main therapeutic area

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Return Partnerships
Recurring site collaborations
0
Sites with multiple studies

Has run more than one trial at 0 of 23 partner sites.

Specializations

Breast Oncology

The investigator concentrates on Hormone Receptor‑Positive and HER2‑Negative disease subtypes, as well as advanced HER2‑positive and triple‑negative tumors.

  • Advanced/metastatic breast carcinoma
  • Early‑stage hormone‑responsive breast cancer
  • HER2‑low and HER2‑overexpressing tumors
  • Triple‑negative breast cancer

Research supports therapeutic strategies that integrate endocrine agents, targeted antibodies, and antibody‑drug conjugates.

Lung Cancer Therapeutics

Focus is placed on both small‑cell and non‑small‑cell lung malignancies, including molecularly defined subgroups.

  • Small‑cell lung carcinoma (SCLC)
  • EGFR‑mutated non‑small‑cell lung cancer
  • ALK‑positive and ROS1‑rearranged NSCLC
  • Brain‑metastatic lung cancer

Efforts aim to expand treatment options for patients requiring second‑line or later therapy.

Metabolic Liver Disease

Investigation includes the progressive form of fatty liver disease, Non‑Alcoholic Steatohepatitis (NASH), and its complications.

  • NASH with fibrosis
  • NAFLD‑related cirrhosis
  • Hepatocellular carcinoma arising from steatohepatitis
  • Metabolic risk factors such as obesity and type‑2 diabetes

Therapeutic research targets inflammation, lipid metabolism, and fibrotic pathways.

Cardiovascular and Heart Failure

Clinical work addresses atherosclerotic disease, elevated lipoprotein(a), and diverse heart‑failure phenotypes.

  • Atherosclerotic cardiovascular disease (ASCVD)
  • Elevated lipoprotein(a) risk
  • Heart failure with reduced ejection fraction
  • Heart failure with preserved ejection fraction

Investigations seek to modify disease progression and improve cardiac outcomes.

Autoimmune and Rheumatologic Disorders

The investigator also contributes to studies of systemic and cutaneous autoimmune conditions.

  • Systemic lupus erythematosus
  • Cutaneous lupus erythematosus
  • Psoriatic arthritis
  • Rheumatoid arthritis

Efforts focus on disease‑modifying agents that target inflammatory pathways.

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