Manuel D. M. M.
- Country
- Spain
- Department
- Servicio de Cardiología
Research Overview
Data & Insights
Has run more than one trial at 0 of 5 partner sites.
Specializations
Coronary Artery Disease & Revascularization
Focused on the diagnosis, interventional management, and long‑term outcomes of patients with obstructive coronary pathology.
- Coronary Artery Disease in patients undergoing percutaneous coronary intervention
- Assessment of stable coronary syndromes following successful PCI
- Management of spontaneous coronary artery dissection in acute settings
Research integrates imaging, biomarker, and pharmacologic strategies to improve myocardial reperfusion and reduce recurrent events.
Heart Failure & Ventricular Dysfunction
Investigation of mechanisms and therapies for systolic heart failure across diverse etiologies.
- Therapeutic evaluation in heart failure due to systemic left ventricular systolic dysfunction
- Early intervention with candesartan to prevent left ventricular remodeling
- Outcomes research in patients with advanced heart failure requiring device therapy
Emphasis on optimizing guideline‑directed medical therapy and novel agents to halt disease progression.
Genetic Cardiomyopathies & Inherited Cardiac Disorders
Targeted studies on hereditary conditions that predispose to cardiac dysfunction.
- Screening of genetic carriers of dilated cardiomyopathy variants
- Phenotypic characterization of familial hypertrophic cardiomyopathy
- Risk stratification in arrhythmogenic right ventricular cardiomyopathy
Efforts aim to define early biomarkers and preventive strategies for at‑risk populations.
Vascular Medicine & Atherosclerotic Prevention
Study of systemic vascular health and primary prevention of atherothrombotic events.
- Evaluation of primary prevention of atherosclerotic cardiovascular disease in high‑risk cohorts
- Impact of lipid‑lowering therapies on major adverse cardiovascular events
- Role of anti‑inflammatory agents in reducing vascular inflammation
Integrates clinical risk modeling with emerging therapeutic modalities.
Cardiac Imaging & Biomarker Development
Advancement of diagnostic tools to refine cardiovascular disease assessment.
- Utilization of advanced echocardiography in cardiac remodeling detection
- Validation of circulating troponin and NT‑proBNP as prognostic markers
- Integration of cardiac MRI for tissue characterization in ischemic heart disease
Supports precision medicine approaches in cardiology.
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