Maité Lacou A.
- Country
- France
- Department
- Intensive care
Research Overview
Data & Insights
Has run more than one trial at 3 of 14 partner sites.
Specializations
Critical Care and Acute Organ Failure
Clinical research in intensive care medicine includes sepsis, acute respiratory distress syndrome, post-cardiac arrest syndrome, shock, and severe acute kidney injury, with attention to unstable patients requiring advanced organ support.
- Sepsis and septic shock
- Acute respiratory failure and ARDS
- Cardiac arrest and post-resuscitation care
- Acute kidney injury in critical illness
The therapeutic scope also covers mechanical ventilation, vasoplegic shock, and complex postoperative critical care situations.
Hematologic Malignancies and Cellular Therapy
Research activity is strongly centered on acute leukemia, myelodysplastic syndromes, lymphoma, multiple myeloma, and graft-versus-host disease, including patients undergoing allogeneic hematopoietic stem cell transplantation.
- Acute lymphoblastic leukemia and acute myeloid leukemia
- Myelodysplastic syndromes and myelofibrosis
- B-cell lymphoma and mantle cell lymphoma
- Stem cell transplantation and graft-versus-host disease
The portfolio extends to relapsed and refractory hematologic cancers, minimal residual disease strategies, and transplant-related immune complications.
Respiratory, Infectious, and Inflammatory Lung Disease
Investigations include non-tuberculous mycobacterial lung infection, chronic pulmonary aspergillosis, pneumonia, bronchiectasis, and chronic obstructive pulmonary disease, alongside broader pulmonary infection and interstitial lung disease topics.
- Mycobacterial and fungal lung infections
- Chronic pulmonary aspergillosis
- Community-acquired and hospital-acquired pneumonia
- Interstitial lung disease and pulmonary fibrosis
Therapeutic interest also includes antimicrobial treatment, antifungal therapy, and management of respiratory infections in vulnerable patients.
Autoimmune, Renal, and Transplant-Related Disorders
Clinical studies address vasculitis, systemic lupus erythematosus, lupus nephritis, IgA nephropathy, glomerulonephritis, and kidney transplantation, reflecting a strong interest in immune-mediated organ injury.
- ANCA-associated vasculitis and giant cell arteritis
- Systemic lupus erythematosus and lupus nephritis
- IgA nephropathy and chronic kidney disease
- Kidney transplant rejection and transplant complications
Additional focus includes immune thrombocytopenia, autoimmune hemolytic anemia, and post-transplant immune dysregulation.
Cardiovascular, Neurologic, and Metabolic Conditions
Research involvement also spans acute coronary syndrome, heart failure, atrial fibrillation, stroke, migraine, and neurodegenerative disease, together with selected metabolic and liver disorders.
- Acute coronary syndrome and heart failure
- Stroke and cardiac arrest
- Multiple sclerosis and Alzheimer’s disease
- Metabolic liver disease and obesity
The therapeutic landscape includes cardiovascular risk reduction, neurologic symptom control, and treatment of inflammatory metabolic disease.
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