Maike H.
- Country
- Germany
- Department
- Internal Medicine III, Hematology and Oncology
Research Overview
- Phase I/II Study on Safety and Efficacy of AZD5492 as Monotherapy and in Combination for Relapsed/Refractory B-Cell Malignancies
- Venetoclax in combination with the BTK inhibitor Ibrutinib and Rituximab or conventional chemotherapy (Bendamustine) and Ibrutinib and Rituximab in patients with treatment naive Mantle Cell Lymphoma not eligible for high dose therapy
- A Phase 3 Randomized Study Comparing Odronextamab and Lenalidomide Versus Rituximab and Lenalidomide in Relapsed/Refractory Follicular and Marginal Zone Lymphoma
Data & Insights
Has run more than one trial at 88 of 279 partner sites.
Specializations
Myeloid malignancies
Clinical research in acute myeloid leukemia, myelodysplastic syndromes, chronic myelomonocytic leukemia, and myelofibrosis, with attention to relapsed or refractory disease, high-risk subtypes, and treatment resistance.
- Acute myeloid leukemia
- Myelodysplastic syndromes
- Chronic myelomonocytic leukemia
- Myelofibrosis
Work in this area also includes stem cell transplantation and post-transplant disease management in hematologic cancer.
Lymphoid malignancies and plasma cell disorders
Active involvement in trials for non-Hodgkin lymphoma, Hodgkin lymphoma, chronic lymphocytic leukemia, multiple myeloma, and acute lymphoblastic leukemia, including aggressive, relapsed, and high-risk presentations.
- Diffuse large B-cell lymphoma
- Follicular lymphoma
- Multiple myeloma
- Acute lymphoblastic leukemia
Research interests extend to cellular therapy and gene-modified T cells in hematologic cancers.
Solid tumors in gastrointestinal and hepatobiliary oncology
Clinical trial activity spans gastric cancer, gastroesophageal junction adenocarcinoma, esophageal cancer, colorectal cancer, pancreatic cancer, and hepatocellular carcinoma, with additional focus on biliary tract cancer and neuroendocrine tumors.
- Gastric and gastroesophageal junction cancer
- Pancreatic ductal adenocarcinoma
- Colorectal cancer
- Hepatocellular carcinoma
Investigator involvement reflects interest in perioperative oncology, metastatic disease, and biomarker-driven treatment strategies.
Genitourinary and thoracic oncology
Research includes prostate cancer, renal cell carcinoma, urothelial carcinoma, bladder cancer, non-small cell lung cancer, and small cell lung cancer, covering both localized and advanced disease settings.
- Prostate cancer
- Renal cell carcinoma
- Urothelial carcinoma
- Non-small cell lung cancer
Therapeutic interests also include immune checkpoint inhibition and targeted treatment in advanced solid tumors.
Inflammatory, neurologic, and supportive care conditions
Clinical involvement extends to Crohn’s disease, atopic dermatitis, psoriasis, myasthenia gravis, multiple sclerosis, Alzheimer’s disease, and amyotrophic lateral sclerosis, alongside supportive care topics such as chronic pain and anemia.
- Crohn’s disease
- Multiple sclerosis
- Myasthenia gravis
- Chronic pain syndromes
Additional interests include infectious disease prevention, kidney transplantation, and cardiovascular complications in medically complex patients.
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