Mahmoud M.
- Country
- Germany
- Department
- Klinik für Internistische Onkologie und Hämatologie
Research Overview
Data & Insights
Has run more than one trial at 60 of 79 partner sites.
Specializations
Non‑Small Cell Lung Cancer
The investigator focuses on advanced and resectable forms of Non‑Small Cell Lung Cancer, including EGFR‑mutated and KRAS‑mutant subtypes.
- Targeted kinase inhibition
- PD‑L1 directed immunotherapy
- Neoadjuvant and adjuvant chemo‑immunotherapy
- Biomarker‑driven patient selection
Research integrates molecular profiling to refine therapeutic strategies for Non‑Small Cell Lung Cancer.
Small Cell Lung Cancer
Clinical work addresses extensive‑stage and relapsed Small Cell Lung Cancer, evaluating novel agents and combination regimens.
- Antibody‑drug conjugates
- Combination chemotherapy with novel agents
- Immune checkpoint blockade
- Second‑line therapeutic options
Efforts aim to improve survival outcomes in patients with Small Cell Lung Cancer.
Neuroendocrine Tumors
The investigator evaluates therapies for well‑differentiated metastatic Neuroendocrine Tumors of pancreatic and gastrointestinal origin.
- Peptide receptor radionuclide therapy
- Anti‑angiogenic combinations
- Targeted molecular agents
- Symptom control for carcinoid syndrome
Clinical studies seek to extend progression‑free intervals in Neuroendocrine Tumors.
Idiopathic Pulmonary Fibrosis
Research targets progressive fibrotic lung disease, specifically Idiopathic Pulmonary Fibrosis and related pulmonary fibrosis phenotypes.
- Inhaled prostacyclin analogues
- Antifibrotic small molecules
- Long‑term safety assessments
- Functional decline mitigation
Therapeutic evaluation focuses on preserving lung capacity in patients with Idiopathic Pulmonary Fibrosis.
Cardiovascular Disease
The investigator contributes to trials addressing lipid disorders and cardiovascular risk, including Hypercholesterolemia and lipoprotein(a)–mediated disease.
- LDL‑C lowering agents
- Lipoprotein(a) reduction strategies
- Cardiovascular event prevention
- Safety profiling in high‑risk cohorts
Efforts aim to lower major adverse cardiac events in individuals with Cardiovascular Disease.
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