Magdalena T. G.
- Country
- Poland
- Department
- Neurology with Stroke Unit
Research Overview
- A Phase 3, Randomized, Double-Blind, Parallel-Group, Placebo-Controlled Study to Demonstrate the Efficacy and Safety of Milvexian, an Oral Factor XIa Inhibitor, for Stroke Prevention after an Acute Ischemic Stroke or High-Risk Transient Ischemic Attack
- Phase 2/3 Adaptive Design, Randomized Double-blind Placebo-controlled Study to Evaluate the Safety and Efficacy of DM199 for the Treatment of Acute Ischemic Stroke (ReMEDy2 Trial)
Data & Insights
Has run more than one trial at 18 of 256 partner sites.
Specializations
Stroke and Acute Neurology
Clinical research activity includes treatment strategies for acute ischemic stroke, high-risk transient ischemic attack, and refractory status epilepticus, with attention to urgent neurological care and prevention of secondary injury.
- Acute ischemic stroke
- High-risk transient ischemic attack
- Refractory status epilepticus
Therapeutic interest also extends to interventions for myocardial injury after non-cardiac surgery and perioperative circulatory instability in patients with vascular risk.
Neuroimmunology and Neurodegeneration
The investigator is involved in studies addressing myasthenia gravis and frontotemporal dementia linked to progranulin mutations, reflecting a focus on immune-mediated and degenerative disorders of the nervous system.
- Myasthenia gravis
- Frontotemporal dementia
- Progranulin mutations
Additional interest includes neurological conditions with episodic symptom burden such as migraine, spanning both episodic migraine and chronic migraine.
Thyroid Eye Disease and Ophthalmic Inflammation
Research activity centers on thyroid eye disease, including moderate-to-severe active thyroid eye disease and thyroid eye disease with proptosis-related outcomes, alongside related inflammatory orbitopathy.
- Thyroid eye disease
- Proptosis
- Inflammatory orbitopathy
This area also connects with ophthalmic preservation of function in dry age-related macular degeneration with geographic atrophy.
Gastroenterology and Hepatobiliary Disease
The investigator participates in therapeutic studies for chronic inflammatory and cholestatic disorders, including primary biliary cholangitis, primary sclerosing cholangitis, and moderately to severely active Crohn's disease.
- Primary biliary cholangitis
- Primary sclerosing cholangitis
- Crohn's disease
Related interests include non-alcoholic steatohepatitis and pancreatic exocrine insufficiency, covering liver, bowel, and pancreatic therapeutic needs.
Oncology and Systemic Therapeutics
Clinical trial involvement spans multiple solid-tumor settings, including non-small cell lung cancer, gastric cancer, head and neck squamous cell carcinoma, breast cancer, and advanced solid tumors.
- Non-small cell lung cancer
- Gastric cancer
- Head and neck squamous cell carcinoma
Additional oncology interests include biliary tract cancer, neuroendocrine tumors, and endometrial cancer, with emphasis on immunotherapy and targeted treatment domains.
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