Magda H.
- Country
- Czechia
- Department
- Neurologická klinika
Research Overview
- A Phase 3, Randomized, Double-Blind, Placebo-Controlled Study of Empasiprubart in Adults With Chronic Inflammatory Demyelinating Polyneuropathy (CIDP)
- A Phase 3, Randomized, Double-Blinded, Double-Dummy Study Evaluating the Efficacy and Safety of Intravenous Empasiprubart Versus Intravenous Immunoglobulin in Adults With Chronic Inflammatory Demyelinating Polyneuropathy
Data & Insights
Has run more than one trial at 25 of 76 partner sites.
Specializations
Hematologic malignancies
Clinical research activity includes a broad focus on blood cancers, with involvement in acute myeloid leukemia, acute lymphoblastic leukemia, multiple myeloma, chronic lymphocytic leukemia, and lymphoma subtypes. The portfolio also extends to myelodysplastic syndromes, myelofibrosis, and other myeloid neoplasms.
- Acute myeloid leukemia
- Multiple myeloma
- Chronic lymphocytic leukemia
- Diffuse large B-cell lymphoma
- Myelodysplastic syndromes
Interest also covers relapsed and refractory hematologic disease, transplant-related maintenance strategies, and targeted approaches in plasma cell disorders and B-cell malignancies.
Neuroimmunology and neuromuscular disease
Research involvement includes disorders of the central nervous system and immune-mediated neurology, with attention to multiple sclerosis, myasthenia gravis, chronic inflammatory demyelinating polyneuropathy, and amyotrophic lateral sclerosis. The clinical scope also includes selected seizure disorders and other nervous system diseases.
- Multiple sclerosis
- Generalized myasthenia gravis
- Chronic inflammatory demyelinating polyneuropathy
- Amyotrophic lateral sclerosis
- Ocular myasthenia gravis
Additional therapeutic interest includes rare neurological disorders and conditions requiring long-term disease control within specialized neurology care.
Cardiovascular and hemostatic medicine
Clinical trial activity spans acute myocardial infarction, heart failure, atherosclerotic cardiovascular disease, atrial fibrillation, and vascular disease. The investigator is also involved in studies addressing hemophilia, immune thrombocytopenia, and anticoagulation-related bleeding management.
- Acute myocardial infarction
- Heart failure
- Atherosclerotic cardiovascular disease
- Hemophilia A and B
- Anticoagulation reversal
Therapeutic interests also include thrombotic risk reduction, cardiovascular event prevention, and supportive care for patients with bleeding or clotting disorders.
Autoimmune, inflammatory, and allergic disorders
Research engagement includes ulcerative colitis, Crohn's disease, asthma, atopic dermatitis, psoriatic arthritis, and other immune-mediated diseases. The therapeutic landscape also covers primary immunodeficiency and selected systemic inflammatory conditions.
- Inflammatory bowel disease
- Severe asthma
- Atopic dermatitis
- Psoriatic arthritis
- Primary immunodeficiency diseases
There is also involvement in eosinophilic and autoimmune conditions where targeted immunomodulation is clinically relevant.
Oncology and rare pediatric diseases
The clinical research profile includes solid tumors such as breast cancer, lung cancer, ovarian cancer, endometrial cancer, and renal cell carcinoma, alongside pediatric malignancies including medulloblastoma, neuroblastoma, and sarcomas. Rare disease interests also extend to Langerhans cell histiocytosis and genetic metabolic disorders.
- Breast cancer
- Non-small cell lung cancer
- Ovarian cancer
- Medulloblastoma
- Langerhans cell histiocytosis
Therapeutic interest includes targeted oncology, immunotherapy, and treatment options for rare and relapsed cancers across adult and pediatric populations.
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