Madeleine P.
- Country
- France
- Department
- ONCO-RADIOTHERAPIST
Research Overview
- Phase III Randomized Study of Induction Chemotherapy with Modified DCF Regimen Followed by Chemoradiotherapy vs. Standard Chemoradiotherapy in Locally Advanced Anal Squamous Cell Carcinoma
- Neoadjuvant Dostarlimab and Short-Course Radiotherapy in Microsatellite Unstable or Mismatch Repair-Deficient Locally Advanced Rectal Cancer
Data & Insights
Has run more than one trial at 41 of 128 partner sites.
Specializations
Gastrointestinal Oncology
The investigator specializes in treating complex gastrointestinal cancers, with particular focus on rectal cancer and anal squamous cell carcinoma. Their expertise extends to managing locally advanced cases requiring sophisticated treatment approaches.
- Advanced Rectal Cancer Management
- Anal Cancer Treatment Strategies
- Gastrointestinal Tumor Therapy
Demonstrates particular interest in microsatellite unstable and mismatch repair-deficient tumor variants.
Radiation Oncology
Shows expertise in implementing innovative radiotherapy protocols, including short-course radiation treatments and chemoradiotherapy combinations for gastrointestinal malignancies.
- Combined Modality Treatment
- Advanced Radiation Protocols
- Therapeutic Response Assessment
Incorporates both standard and novel radiation approaches in treatment planning.
Immunotherapy Applications
Focuses on implementing immunotherapeutic approaches in gastrointestinal cancers, particularly utilizing dostarlimab in neoadjuvant settings. Explores watch-and-wait strategies in combination with immunotherapy.
- Neoadjuvant Immunotherapy
- Treatment Response Monitoring
- Novel Therapeutic Combinations
Specializes in personalized treatment approaches based on tumor molecular characteristics.
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