Macarena G. C.
- Country
- Spain
- Department
- Pediatric Oncology and Haematology Unit
Research Overview
- Phase II Multicohort Study of Trabectedin and Low-Dose Radiation Therapy in Advanced/Metastatic Soft Tissue and Bone Sarcomas
- Evaluation of Chemotherapy Regimens Including Cisplatin, Cyclophosphamide, and Etoposide in Pediatric and Young Adult Ependymoma Treatment
- Evaluation of Carboplatin and Chemotherapeutic Regimen in Pediatric Patients with Standard-Risk and High-Risk Medulloblastoma: A Multinational Prospective Study
Data & Insights
Has run more than one trial at 131 of 209 partner sites.
Specializations
Paediatric Haematology and Rare Blood Disorders
Macarena González is involved in clinical research on multiple myeloma, smoldering multiple myeloma, light chain amyloidosis, myelofibrosis, and acute myeloid leukemia, with attention to treatment options for both newly diagnosed and relapsed disease. Her trial portfolio also includes immune thrombocytopenia and other complex haematologic conditions.
- Multiple myeloma
- Light chain amyloidosis
- Myelofibrosis
- Acute myeloid leukemia
Her research activity in this field is centred on therapeutic innovation for plasma cell and marrow disorders, including approaches linked to minimal residual disease and long-term disease control.
Breast Cancer and Hormone-Driven Malignancies
She is actively engaged in studies of early breast cancer, metastatic breast cancer, HER2-positive breast cancer, HER2-negative breast cancer, and triple-negative breast cancer, including disease defined by PIK3CA and ESR1 alterations. Her work also extends to hormone receptor-positive and endocrine-resistant breast cancer.
- Early breast cancer
- Metastatic breast cancer
- HER2-positive breast cancer
- Hormone receptor-positive breast cancer
Her therapeutic focus includes targeted treatment strategies, endocrine-based regimens, and antibody-drug conjugate approaches in breast oncology.
Paediatric Oncology and Solid Tumours
Her clinical research includes soft tissue sarcoma, bone sarcoma, Ewing sarcoma, rhabdomyosarcoma, hepatoblastoma, hepatocellular carcinoma, medulloblastoma, ependymoma, and Langerhans cell histiocytosis, reflecting a broad interest in paediatric and adolescent solid tumours and histiocytic disease.
- Soft tissue sarcoma
- Bone sarcoma
- Medulloblastoma
- Langerhans cell histiocytosis
Her research landscape also includes advanced and metastatic tumour settings, with emphasis on novel systemic therapies for difficult-to-treat malignancies.
Autoimmune and Inflammatory Disease
Macarena González participates in studies of systemic lupus erythematosus, lupus nephritis, Sjögren’s syndrome, psoriatic arthritis, juvenile psoriatic arthritis, idiopathic inflammatory myopathies, giant cell arteritis, and Crohn's disease, along with non-infectious uveitis and severe eosinophilic asthma.
- Systemic lupus erythematosus
- Sjögren’s syndrome
- Psoriatic arthritis
- Idiopathic inflammatory myopathies
Her therapeutic interests span immune modulation, inflammatory control, and organ-specific disease management across rheumatology, gastroenterology, and respiratory medicine.
Respiratory, Cardiometabolic, and Transplant-Related Conditions
Her trial involvement also covers non-small cell lung cancer, small cell lung cancer, allergic rhinitis, asthma, obesity, type 2 diabetes, atherosclerotic cardiovascular disease, statin-associated risk, kidney transplantation, and primary hyperoxaluria.
- Asthma and allergic disease
- Atherosclerotic cardiovascular disease
- Kidney transplantation
- Metabolic disease
Her research activity reflects interest in prevention and treatment strategies for cardiometabolic risk, airway inflammation, and transplant-associated metabolic complications.
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