M.F. D.
- Country
- The Netherlands
- Department
- Hematology
Research Overview
- Phase 2 Evaluation of Golcadomide (CC-99282) in Relapsed/Refractory Primary and Secondary Central Nervous System Large B-Cell Lymphoma
- HOVON 152 DLBCL. A phase II study evaluating the effect of DA-EPOCH-R induction followed by nivolumab consolidation in patients with newly diagnosed high grade B cell lymphoma (HGBL) with MYC and BCL2 and/or BCL6 rearrangements
Data & Insights
Has run more than one trial at 5 of 29 partner sites.
Specializations
Cardiovascular Medicine
The investigator concentrates on atherosclerotic and thrombotic conditions, including coronary and peripheral vascular disease.
- Acute myocardial infarction
- Atherosclerotic cardiovascular disease
- Peripheral arterial disease
- Statin intolerance
- Inclisiran therapy
Research activities aim to improve outcomes for patients at high cardiovascular risk.
Oncology – Solid Tumors
Focused on targeted and immunotherapeutic strategies for a range of solid malignancies.
- Non‑small cell lung cancer
- Metastatic breast cancer
- Advanced colorectal cancer
- Prostate cancer with PTEN deficiency
- Gastric and esophageal adenocarcinoma
Clinical work integrates novel agents with standard regimens to enhance survival.
Hematologic Malignancies
Engaged in trials addressing lymphoid and plasma‑cell disorders.
- Diffuse large B‑cell lymphoma
- Chronic lymphocytic leukemia
- Multiple myeloma
- Follicular lymphoma
- Small lymphocytic lymphoma
Efforts target durable remission through combination immunotherapies.
Gastroenterology & Hepatology
Specializes in inflammatory bowel disease and metabolic liver disorders.
- Crohn’s disease
- Ulcerative colitis
- Non‑alcoholic steatohepatitis
- Metabolic dysfunction‑associated steatohepatitis
- Early stage colorectal cancer
Studies evaluate biologic agents and disease‑modifying strategies.
Infectious & Immune‑Mediated Disorders
Investigates viral infections and autoimmune conditions with novel immunomodulators.
- HIV infection
- Rheumatoid arthritis
- Psoriatic arthritis
- Polymyalgia rheumatica
- Statin intolerance management
Trials explore safety and efficacy of targeted therapies across immune pathways.
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