Lysiane M.
- Country
- France
- Department
- Clinical Hematology
Research Overview
- A Phase III, Randomized, Open-label, Clinical Trial to Compare Pembrolizumab with Brentuximab Vedotin in Subjects with Relapsed or Refractory Classical Hodgkin Lymphoma
- Efficacy and Safety Comparison of Obinutuzumab-Venetoclax vs. Obinutuzumab-Chlorambucil in Untreated CLL with Comorbidities
- A phase 3, multicenter, randomized, double-blind, placebo-controlled trial comparing the efficacy and safety of tafasitamab plus lenalidomide in addition to R-CHOP versus R CHOP in previously untreated, high-intermediate and high-risk patients with newly-diagnosed diffuse large B-cell lymphoma (DLBCL) [frontMIND]
Data & Insights
Has run more than one trial at 86 of 233 partner sites.
Specializations
Lymphoma Research
The investigator specializes in treating various forms of lymphoma, with particular focus on diffuse large B-cell lymphoma (DLBCL) and classical Hodgkin lymphoma. Their research encompasses both newly diagnosed and relapsed/refractory cases.
- First-line DLBCL treatments
- Advanced classical Hodgkin lymphoma therapy
- Novel combination therapies
Work includes evaluating innovative therapeutic combinations incorporating targeted agents like polatuzumab vedotin and brentuximab vedotin.
Leukemia Studies
Focuses on advancing treatment options for Chronic Lymphocytic Leukemia (CLL), with particular attention to elderly patients and those with coexisting medical conditions.
- High-risk CLL management
- Targeted therapy approaches
- Age-specific treatment strategies
Investigates novel therapeutic agents including venetoclax, obinutuzumab, and acalabrutinib for CLL treatment.
Therapeutic Innovation
Explores cutting-edge treatment combinations incorporating immunotherapy and targeted therapeutic approaches for hematologic malignancies.
- Combination therapy development
- Treatment optimization studies
- Progressive disease management
Evaluates treatment efficacy through progression-free survival outcomes across various therapeutic regimens.
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