Lukasz H.
- Country
- Poland
- Department
- NA
Research Overview
- Efficacy and Safety Evaluation of Paltusotine in Adults with Carcinoid Syndrome Secondary to Well-Differentiated Neuroendocrine Tumors: A Randomized, Placebo-Controlled Trial
- Phase 3 Randomized Study of Zolbetuximab, Pembrolizumab, and Chemotherapy in HER2-Negative, CLDN18.2-Positive, PD-L1-Positive Gastric Adenocarcinoma
- Efficacy and Safety of NGM120 in Colorectal Cancer Patients with Cancer Cachexia: A Phase 2 Randomized, Double-Blind, Placebo-Controlled Study
Data & Insights
Has run more than one trial at 66 of 217 partner sites.
Specializations
Rheumatology and Autoimmune Disease
Clinical research activity includes inflammatory joint and connective tissue disorders, with involvement in rheumatoid arthritis, psoriatic arthritis, axial spondyloarthritis, systemic lupus erythematosus, and Sjögren’s syndrome. The portfolio also extends to systemic sclerosis and related rheumatologic conditions.
- Rheumatoid arthritis
- Systemic lupus erythematosus
- Psoriatic arthritis
- Sjögren’s syndrome
- Systemic sclerosis
Interest is centered on immune-mediated disease control and therapeutic options for chronic systemic inflammation.
Cardiovascular Medicine and Metabolic Risk
Research involvement covers atherosclerotic cardiovascular disease, atrial fibrillation, heart failure, myocardial infarction, hypertension, and lipid-related disorders such as hypertriglyceridemia and elevated lipoprotein(a). Studies also reflect interest in type 2 diabetes mellitus, obesity, and broader cardiometabolic prevention.
- Atherosclerotic cardiovascular disease
- Heart failure
- Hypertriglyceridemia
- Type 2 diabetes mellitus
- Obesity
The therapeutic focus includes reduction of vascular risk and management of chronic cardiometabolic burden.
Oncology and Hematologic Malignancies
Trial activity spans solid tumors and blood cancers, including non-small cell lung cancer, small-cell lung cancer, breast cancer, gastric cancer, urothelial carcinoma, and prostate cancer. Hematology-related interest also includes multiple myeloma, myelofibrosis, and acute lymphoblastic leukemia.
- Non-small cell lung cancer
- Breast cancer
- Urothelial carcinoma
- Multiple myeloma
- Myelofibrosis
This area reflects engagement with advanced malignancies and treatment strategies across both solid and hematologic oncology.
Gastroenterology and Hepatology
Research participation includes Crohn’s disease, ulcerative colitis, celiac disease, primary biliary cholangitis, and metabolic dysfunction-associated steatohepatitis. The portfolio also covers gastroesophageal reflux disease and other chronic digestive and liver disorders.
- Crohn’s disease
- Ulcerative colitis
- Primary biliary cholangitis
- Metabolic dysfunction-associated steatohepatitis
- Celiac disease
The therapeutic landscape emphasizes immune-driven gastrointestinal disease and chronic liver injury.
Neurology, Dermatology, and Respiratory Disease
Additional research areas include migraine, focal epilepsy, trigeminal neuralgia, and Parkinson’s disease, alongside dermatologic conditions such as atopic dermatitis, chronic spontaneous urticaria, vitiligo, and hidradenitis suppurativa. Respiratory involvement includes chronic obstructive pulmonary disease and respiratory syncytial virus-related disease.
- Migraine
- Focal epilepsy
- Atopic dermatitis
- Vitiligo
- Chronic obstructive pulmonary disease
These interests span symptom control, inflammatory skin disease, neurotherapeutics, and chronic airway disease.
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