Luis G. H.
- Country
- Spain
- Department
- Pediatría
Research Overview
Data & Insights
Has run more than one trial at 0 of 8 partner sites.
Specializations
Nephrology and Renal Therapeutics
Investigations target chronic kidney disease progression, proteinuria reduction, and immunoglobulin‑mediated renal disorders.
- Finerenone in CKD without RAS inhibition
- Atrasentan combined with SGLT2 inhibitors
- Felzartamab for IgA nephropathy
- NNC0519‑0130 dose‑response on albuminuria
Emphasis lies on novel renal protective strategies and biomarker‑driven outcomes.
Respiratory and Critical Care Medicine
Clinical work includes acute respiratory distress syndrome and thrombo‑embolic pulmonary events in critically ill patients.
- Oxygen therapy for intermediate‑risk pulmonary embolism
- Intravenous plasma gelsolin in ARDS
- Inhaled sedation versus intravenous propofol
- Pneumococcal vaccine efficacy against community‑acquired pneumonia
Projects aim to improve respiratory support and infection prevention in acute settings.
Neurology, Psychiatry and Cognitive Disorders
Research addresses Alzheimer’s disease‑related neuropsychiatric symptoms and demyelinating conditions.
- ITI‑1284 for psychosis in Alzheimer’s disease
- ITI‑1284 for agitation in Alzheimer’s dementia
- Remibrutinib versus teriflunomide in multiple sclerosis
- Iclepertin safety in schizophrenia with cognitive impairment
Focus is on symptom control and disease‑modifying therapies for neurocognitive disorders.
Rheumatology, Bone Health and Metabolic Disorders
Studies explore therapeutic options for rheumatoid arthritis, bone fragility, and metabolic disease.
- Romosozumab versus bisphosphonates in osteogenesis imperfecta
- Baricitinib comparative safety regarding venous thromboembolism
- Colchicine for cardiovascular event prevention in CKD
- Upadacitinib for vitiligo (non‑segmental)
Efforts aim to balance efficacy with safety across inflammatory and skeletal conditions.
Infectious Diseases and Immunization
Clinical focus includes HIV infection management and pneumococcal vaccine development.
- VH4524184 oral regimens versus DTG/3TC in treatment‑naïve HIV‑1
- V116 immunogenicity and safety in older adults
- 20‑valent pneumococcal conjugate vaccine effectiveness
- Outpatient antibiotic‑free management of uncomplicated diverticulitis
Initiatives target antiviral efficacy, vaccine‑induced protection, and antimicrobial stewardship.
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