Ludmila B.
- Country
- Czechia
- Department
- Fakultní nemocnice Královské Vinohrady, Diabetologické centrum, Šrobárova 1150/50,Praha 10,100 34
Research Overview
- Efficacy and Safety of MET097 in Adults with Overweight or Obesity: A Phase 3, Randomized, Placebo-Controlled Trial
- Phase 3 Randomized, Placebo‑Controlled Trial Assessing Efficacy and Safety of MET097, a Long‑Acting GLP‑1 Receptor Agonist, in Overweight/Obese Adults with Type 2 Diabetes
- Evaluation of Maridebart Cafraglutide Efficacy and Safety in Adults with Obesity or Overweight Without Type 2 Diabetes Mellitus: A Phase 3 Randomized, Double-blind, Placebo-controlled Study
Data & Insights
Has run more than one trial at 119 of 196 partner sites.
Specializations
Diabetes and Retinal Complications
Ludmila Brunerová is involved in clinical research centred on diabetology, with a clear focus on the management of type 1 diabetes and type 2 diabetes alongside their ocular complications. Her trial activity includes studies addressing diabetic macular edema, diabetic retinopathy, age-related macular degeneration, and other vision-threatening retinal disorders.
- Diabetic macular edema
- Diabetic retinopathy
- Type 1 diabetes
- Type 2 diabetes
- Age-related macular degeneration
Her research landscape also includes ophthalmic outcomes linked to metabolic disease and therapies aimed at preserving retinal function in chronic diabetes.
Hematologic Malignancies
Her oncology-related trial portfolio is strongly represented by hematologic malignancies, especially lymphoma, multiple myeloma, and leukemia. The disease spectrum includes follicular lymphoma, diffuse large B-cell lymphoma, chronic lymphocytic leukemia, mantle cell lymphoma, and Hodgkin lymphoma.
- Follicular lymphoma
- Diffuse large B-cell lymphoma
- Chronic lymphocytic leukemia
- Multiple myeloma
- Hodgkin lymphoma
She is also involved in research on myelodysplastic syndromes, myelofibrosis, and other B-cell neoplasms, reflecting a sustained therapeutic interest in blood cancers.
Solid Tumors and Immuno-Oncology
Another major area of interest is solid tumor research, including breast cancer, ovarian cancer, renal cell carcinoma, prostate cancer, bladder cancer, and melanoma. Her trial involvement also extends to head and neck squamous cell carcinoma, endometrial cancer, cervical cancer, and non-small cell lung cancer.
- Breast cancer
- Ovarian cancer
- Renal cell carcinoma
- Melanoma
- Head and neck squamous cell carcinoma
Her portfolio includes immuno-oncology and targeted treatment areas, with attention to advanced and recurrent disease settings across multiple tumor types.
Autoimmune, Inflammatory, and Dermatologic Disease
Her research also covers autoimmune disease, inflammatory bowel disease, and dermatologic disorders. Key therapeutic areas include ulcerative colitis, Crohn's disease, hidradenitis suppurativa, atopic dermatitis, and plaque psoriasis.
- Ulcerative colitis
- Crohn's disease
- Hidradenitis suppurativa
- Atopic dermatitis
- Plaque psoriasis
She is additionally involved in studies of systemic mastocytosis, immune thrombocytopenia, and related immune-mediated conditions.
Cardiovascular, Renal, and Neurologic Disorders
Her clinical research landscape includes important work in cardiovascular disease, thromboembolic disease, kidney disease, and neurologic disease. Areas of activity include myocardial infarction, atrial fibrillation, heart failure, deep vein thrombosis, IgA nephropathy, and multiple sclerosis.
- Myocardial infarction
- Atrial fibrillation
- Heart failure
- IgA nephropathy
- Multiple sclerosis
Her trial involvement also reaches stroke prevention, anticoagulation reversal, and pulmonary hypertension, showing breadth across major internal medicine domains.
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