Lucie B.
- Country
- France
- Department
- Service de Psychiatrie Centre de Recherche Clinique
Research Overview
- Efficacy and Safety of Psilocybin (COMP360) in Adults with Treatment-Resistant Depression: A Phase III Randomized, Double-Blind, Controlled Trial
- Evaluation of the Efficacy and Safety of Lysergide (MM120) in Adults with Generalized Anxiety Disorder: A Phase 3 Randomized, Double-Blind, Placebo-Controlled Study
- Evaluation of Psilocybin and Trazodone Efficacy in Adult Patients with Treatment-Resistant Depression: A Randomized Controlled Proof-of-Concept Study
Data & Insights
Has run more than one trial at 7 of 42 partner sites.
Specializations
Psychiatry and mental health
Clinical research activity includes major depressive disorder, treatment-resistant depression, treatment-resistant schizophrenia, generalized anxiety disorder, psychosis, insomnia, and alcohol use disorder, with interest in interventions addressing symptom control and relapse prevention.
- Depressive disorders
- Schizophrenia and psychosis
- Anxiety and sleep disorders
- Substance use disorders
Work in this area is linked to psychiatric care and clinical research at Paris-based neuroscience and psychiatry sites.
Neurology and cerebrovascular disease
Research interests extend to ischemic stroke, intracerebral haemorrhage, transient ischemic attack, traumatic brain injury, epilepsy, myasthenia gravis, migraine, and upper limb spasticity, reflecting involvement in acute and chronic neurological conditions.
- Stroke and stroke prevention
- Intracerebral haemorrhage
- Epilepsy and headache disorders
- Neuromuscular disease
The portfolio also includes neurological rehabilitation and vascular-neurology themes relevant to acute brain injury and functional recovery.
Respiratory and interstitial lung disease
Therapeutic activity covers non-small cell lung cancer, idiopathic pulmonary fibrosis, progressive pulmonary fibrosis, interstitial lung disease, pulmonary sarcoidosis, chronic thromboembolic pulmonary hypertension, and lung transplant rejection, with additional focus on severe respiratory failure and pulmonary inflammation.
- Non-small cell lung cancer
- Pulmonary fibrosis
- Sarcoidosis
- Pulmonary hypertension
This area also includes post-transplant lung disease and other chronic pulmonary disorders requiring targeted respiratory care.
Oncology and genitourinary cancer
Oncology research spans prostate cancer, breast cancer, ovarian cancer, colorectal cancer, rectal cancer, bladder cancer, gastric cancer, pancreatic cancer, head and neck cancer, and melanoma, with a strong emphasis on advanced and metastatic disease.
- Prostate cancer
- Breast cancer
- Lung cancer
- Gastrointestinal and gynecologic malignancies
Research also includes biomarker-defined solid tumors and disease settings requiring precision oncology approaches.
Cardiovascular, metabolic, and inflammatory disease
Additional interests include heart failure, cardiac arrest, atherosclerotic cardiovascular disease, peripheral arterial disease, chronic kidney disease, type 2 diabetes, obesity, gout, rheumatoid arthritis, Crohn's disease, and myasthenia gravis.
- Cardiovascular disease
- Kidney and metabolic disease
- Inflammatory and autoimmune disorders
- Thromboembolic and antithrombotic care
The research landscape also covers perioperative and acute-care therapeutic questions across internal medicine and multisystem disease.
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