Luca M.
- Country
- Italy
- Department
- Scienze mediche e chirurgiche- ' Unità Operativa Complessa di Medicina Interna e del Trapianto di Fe
Research Overview
- N1T-MC-MALO: A Master Protocol for a Randomized, Controlled, Clinical Trial of Multiple Pharmacologic Agents in Adult Participants With Metabolic Dysfunction-Associated Steatotic Liver Disease Who Are at Increased Risk of Developing Major Adverse Liver Outcomes (SYNERGY-Outcomes); N1T-MC-TZ01 Tirzepatide in participants with high-risk MASLD; N1T-MC-RT01 Retatrutide in participants with high-risk MASLD
- A Phase IIa, Randomized, Double-blind, Placebo-controlled Study to Evaluate Safety, Tolerability, and Pharmacodynamics of AZD4831 in Participants with Non-cirrhotic Non-alcoholic Steatohepatitis (NASH) with Fibrosis
- Phase 3 Randomized Double-Blind Placebo-Controlled Trial of Efruxifermin in Non-Cirrhotic NASH/MASH with Fibrosis
Data & Insights
Has run more than one trial at 131 of 304 partner sites.
Specializations
Liver Disease Management
This investigator specializes in treating non-alcoholic steatohepatitis (NASH) and associated liver conditions, with particular emphasis on managing liver fibrosis at various stages. Their research encompasses both non-cirrhotic and cirrhotic presentations of liver disease.
- NASH Resolution Strategies
- Fibrosis Management
- Cirrhosis Treatment
Hepatobiliary Disorders
The investigator focuses on treating complex hepatobiliary conditions, including primary biliary cholangitis (PBC) and cholestasis. Their work addresses both the primary disease manifestations and associated symptoms such as fatigue and cognitive dysfunction.
- Biliary Disease Management
- Cholestatic Conditions
- Hepatic Dysfunction
Advanced Therapeutic Approaches
The investigator explores innovative therapeutic interventions for liver diseases, including genetic marker-targeted treatments and combination therapies. Their research includes evaluation of novel compounds for fluid retention and metabolic parameters in liver disease.
- Targeted Molecular Therapies
- Metabolic Liver Disease
- Clinical Outcomes Assessment
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