Lorenzo D. A.
- Country
- Italy
- Department
- USSD Epatologia, Gastroenterologia e Trapianti Pediatrici
Research Overview
- Efficacy and Safety Evaluation of Odevixibat in Pediatric Biliary Atresia Post-Kasai Hepatoportoenterostomy: A Double-Blind, Randomized, Placebo-Controlled Trial
- An Open-label Extension Study to Evaluate Long-term Efficacy and Safety of Odevixibat (A4250) in Children with Biliary Atresia (BOLD-EXT)
- Phase I/II Open-Label Study of GNT0003 for Safety and Efficacy in Severe Crigler-Najjar Syndrome Requiring Phototherapy
Data & Insights
Has run more than one trial at 22 of 36 partner sites.
Specializations
Pediatric Liver Disorders
This investigator specializes in treating severe pediatric liver conditions, with particular focus on biliary atresia and post-surgical management following Kasai hepatoportoenterostomy. Their research encompasses innovative therapeutic approaches for maintaining native liver survival in young patients.
- Biliary Atresia Management
- Post-surgical Care
- Native Liver Preservation
Their work extends to long-term monitoring of liver function and surgical outcomes in pediatric patients.
Rare Genetic Conditions
The investigator focuses on treating rare genetic liver disorders, including Crigler-Najjar syndrome and Alagille syndrome. Their expertise includes evaluating novel therapeutic approaches, including gene therapy interventions and specialized medical treatments.
- Genetic Liver Disorders
- Gene Therapy Applications
- Rare Disease Management
Their research encompasses both innovative treatments and long-term disease management strategies.
Cholestatic Conditions
The investigator has significant expertise in treating cholestatic pruritus and related liver conditions. Their work involves evaluating new therapeutic agents for managing symptoms and improving patient quality of life.
- Pruritus Management
- Cholestatic Disease
- Symptom Control
Their research focuses on developing effective treatments for cholestatic conditions and associated complications.
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