LORENE S.
- Country
- France
- Department
- Oncologie Médicale
Research Overview
Data & Insights
Has run more than one trial at 0 of 6 partner sites.
Specializations
Myeloid Hematologic Malignancies
The investigator leads trials in acute myeloid leukemia and related myeloid neoplasms.
- Relapsed/refractory acute myeloid leukemia
- Myelodysplastic syndrome
- Chronic myelomonocytic leukemia
- Acute lymphoblastic leukemia
- Acute myeloid leukemia with NPM1 mutation
All studies are coordinated through the Institut Paoli‑Calmettes Cancer Centre.
Lymphoid and Plasma‑Cell Disorders
Research includes multiple myeloma and B‑cell lymphomas.
- Chronic lymphocytic leukemia
- Diffuse large B‑cell lymphoma
- Mantle cell lymphoma
- Waldenström’s macroglobulinemia
- Follicular lymphoma
Focus is placed on novel immunotherapeutic approaches.
Breast and Gynecologic Oncology
Clinical programs address advanced breast cancer.
- Hormone receptor‑positive HER2‑negative breast cancer
- Triple‑negative breast cancer
- High‑grade serous ovarian carcinoma
- Endometrial carcinoma
- Cervical squamous carcinoma
Trials incorporate endocrine, targeted, and antibody‑drug conjugate strategies.
Thoracic, Renal and Gastrointestinal Cancers
The investigator studies non‑small cell lung cancer across disease stages.
- Renal cell carcinoma
- Metastatic colorectal cancer
- Pancreatic ductal adenocarcinoma
- Hepatocellular carcinoma
- Gastro‑esophageal adenocarcinoma
Emphasis is on biomarker‑driven targeted and immuno‑oncology therapies.
Immunologic and Transplant‑Related Complications
Additional focus is on graft‑versus‑host disease in hematopoietic stem‑cell transplantation.
- Systemic lupus erythematosus
- Lupus nephritis
- Acute graft‑versus‑host disease
- Chronic graft‑versus‑host disease
- Immune‑mediated cytopenias
Investigations target immune modulation and prophylactic strategies.
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