Nicolas D. L.
- Country
- France
- Department
- Nuclear Medicine Unit
Research Overview
- Evaluation of diagnostic performances of 18F-FDOPA PET KInetics as biomarkers for the improvement of care of MRI Non-contrast enhanced Gliomas : a phase IIIb exploratory trial
- Phase IIb Trial of Everolimus and Lutetium (177Lu) Oxodotreotide in Refractory Grade 2 and 3 Meningioma
- Efficacy and Safety of Radium-223 Dichloride Versus Novel Anti-Hormonal Therapy in Bone-Dominant Metastatic Castration-Resistant Prostate Cancer
Data & Insights
Has run more than one trial at 7 of 44 partner sites.
Specializations
Neuro-Oncology
The investigator specializes in advanced diagnostic imaging and treatment of low-grade gliomas, utilizing innovative PET imaging techniques. Their work involves the evaluation of 18F-FDOPA PET kinetics as diagnostic biomarkers, particularly in cases without MRI contrast enhancement.
- Brain Tumor Diagnostics
- Molecular Imaging
- Glioma Assessment
Their expertise extends to examining histopathological and molecular characteristics in brain tumors.
Intracranial Tumors
The investigator focuses on therapeutic approaches for refractory meningiomas, particularly grades 2 and 3. Their research involves the integration of 177Lu-DOTATATE treatment combined with targeted therapy using everolimus.
- Meningioma Treatment
- Peptide Receptor Radionuclide Therapy
- Combined Therapeutic Approaches
Their work emphasizes novel combination treatments for challenging intracranial tumors.
Urologic Oncology
The investigator conducts research in the treatment of metastatic castrate-resistant prostate cancer, with particular emphasis on bone metastases. Their work evaluates the effectiveness of Radium-223 dichloride compared to antihormonal therapies.
- Prostate Cancer Treatment
- Bone Metastasis Management
- Radiopharmaceutical Therapy
Their research focuses on advanced therapeutic options for progressive prostate cancer.
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