Liesbet H.
- Country
- Belgium
- Department
- Infectioloog
Research Overview
- Non‑inferiority of a 7‑day versus 14‑day oral ciprofloxacin regimen for male urinary tract infection with systemic involvement: a randomized controlled trial
- Non-inferiority of an oral combination therapy versus intravenous antibiotic therapy for the treatment of infective endocarditis: The ROSIE trial
Data & Insights
Has run more than one trial at 1 of 8 partner sites.
Specializations
Inflammatory Bowel Disease and Gastroenterology
Clinical research activity includes therapies for Crohn's disease, ulcerative colitis, pouchitis, eosinophilic esophagitis, and functional gastrointestinal disorders, with attention to chronic intestinal inflammation and symptom control.
- Crohn's disease
- Ulcerative colitis
- Pouchitis
- Functional dyspepsia
- Reflux hypersensitivity
The therapeutic focus also extends to gastro-esophageal reflux disease, short bowel syndrome, and other digestive system conditions requiring targeted medical innovation.
Oncology and Hematologic Malignancies
Research involvement spans a broad range of solid tumors and blood cancers, with particular emphasis on breast cancer, lung cancer, ovarian cancer, colorectal cancer, and urothelial carcinoma, alongside multiple lymphoid and myeloid malignancies.
- Breast cancer
- Non-small cell lung cancer
- Ovarian cancer
- Diffuse large B-cell lymphoma
- Acute myeloid leukemia
Additional therapeutic interest includes gastrointestinal cancers, melanoma, prostate cancer, and multiple myeloma, reflecting engagement with advanced and difficult-to-treat malignancies.
Neurology and Neurodegenerative Disease
Clinical trial activity covers amyotrophic lateral sclerosis, Alzheimer's disease, frontotemporal dementia, Parkinson's disease, epilepsy, and other disorders of the central and peripheral nervous system.
- Amyotrophic lateral sclerosis
- Alzheimer's disease
- Frontotemporal dementia
- Epilepsy
- Parkinson's disease
Work also includes myasthenia gravis, progressive supranuclear palsy, and spinal muscular atrophy, areas linked to unmet needs in neuromuscular and neurodegenerative care.
Autoimmune, Renal, and Transplant Medicine
Investigator activity includes lupus nephritis, systemic lupus erythematosus, rheumatoid arthritis, Sjögren's syndrome, systemic sclerosis, and vasculitis, together with immune-mediated kidney disease.
- Lupus nephritis
- IgA nephropathy
- Chronic kidney disease
- Kidney transplant rejection
- Antibody-mediated rejection
Therapeutic interest also covers glomerular disease, polycystic kidney disease, and transplant-related immune complications, highlighting an emphasis on immune modulation and renal preservation.
Infectious Disease and Respiratory Medicine
Research participation includes nontuberculous mycobacterial lung infection, bronchiectasis, chronic obstructive pulmonary disease, fungal infections, and COVID-19, with a focus on complex pulmonary and systemic infections.
- Nontuberculous mycobacterial lung infection
- Bronchiectasis
- Chronic obstructive pulmonary disease
- Invasive fungal infection
- COVID-19
Additional domains include chronic pulmonary aspergillosis, pneumonia, and urinary tract infection, supporting therapeutic work across infectious complications in medically vulnerable patients.
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