Lieke S.
- Country
- The Netherlands
- Department
- Internal medicine
Research Overview
- Phase 3 Multicenter Trial of Neoadjuvant Ipilimumab and Nivolumab Versus Adjuvant Nivolumab in Patients with Macroscopic Stage III Melanoma
- Phase III Multicenter Randomized Trial of Dose-Reduced Chemotherapy with Fluorouracil, Folinic Acid, Capecitabine, and Oxaliplatin in Metastatic Colorectal Cancer
- Evaluation of Induction Chemotherapy with FOLFOXIRI in High-Risk Locally Advanced Rectal Cancer: A Study on Pathological and Clinical Response Rates
Data & Insights
Has run more than one trial at 15 of 68 partner sites.
Specializations
Colorectal Cancer Research
This investigator specializes in advancing treatment approaches for colorectal cancer, with particular emphasis on both locally advanced rectal cancer and metastatic colorectal cancer.
- Advanced Treatment Protocols
- Chemotherapy Optimization
- Therapeutic Response Assessment
The research focuses on evaluating innovative chemotherapy regimens and their effectiveness in different patient populations.
Geriatric Oncology
The investigator conducts specialized research in age-adapted cancer treatments, particularly examining chemotherapy dosing strategies for older patients with colorectal cancer.
- Dose Optimization
- Treatment Tolerance
- Risk Assessment
Key areas include developing personalized treatment approaches based on individual patient risk profiles.
Treatment Response Evaluation
The investigator focuses on assessing therapeutic outcomes through pathological and clinical response measurements in cancer treatment protocols.
- Response Rate Assessment
- Progressive Disease Monitoring
- Survival Analysis
Research encompasses evaluation of treatment efficacy through various clinical endpoints.
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