Lene B.
- Country
- Denmark
- Department
- Hematology
Research Overview
- A Randomized, Double-blind, Placebo-controlled Phase 3 Trial of Pembrolizumab (MK-3475) Versus Placebo in Participants with Esophageal Carcinoma Receiving Concurrent Definitive Chemoradiotherapy (KEYNOTE 975)
- Phase 3 Multicenter Randomized Study Comparing Efficacy and Safety of Sacituzumab Tirumotecan Versus Physician's Choice in Advanced Gastroesophageal Adenocarcinoma
- Phase 3 Randomized Double-Blind Study of Pembrolizumab Plus Chemotherapy Versus Placebo Plus Chemotherapy in HER2-Negative Advanced Gastric or GEJ Adenocarcinoma
Data & Insights
Has run more than one trial at 85 of 227 partner sites.
Specializations
Gastrointestinal Oncology
Specializes in treating gastric adenocarcinoma and gastroesophageal junction cancer, with particular focus on resectable disease and advanced stages. Investigates innovative therapeutic approaches combining chemotherapy with immunotherapy agents.
- Resectable gastric cancer management
- Neoadjuvant-adjuvant treatment strategies
- Advanced gastric cancer therapies
Explores targeted treatments for HER2-negative and FGFR2b-expressing tumors.
Esophageal Cancer Treatment
Focuses on comprehensive treatment approaches for esophageal carcinoma, including both squamous cell and adenocarcinoma variants. Specializes in combining chemoradiotherapy with immunotherapy interventions.
- Definitive chemoradiotherapy protocols
- HER2-positive esophageal cancer treatment
- Metastatic disease management
Investigates novel therapeutic combinations including targeted therapies and immunological approaches.
Precision Oncology
Specializes in biomarker-driven treatment approaches for gastrointestinal malignancies. Focuses on personalized medicine strategies using molecular targeting and immunotherapy.
- PD-L1 expression-guided therapy
- FGFR2b-targeted treatments
- Biomarker-based patient selection
Develops treatment strategies based on specific molecular and genetic tumor characteristics.
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