Leblanc A.
- Country
- Portugal
- Department
- Allergy and Clinical Inmunology
Research Overview
- Bioequivalence Study of Vortioxetine 5 mg Film-Coated Tablets in Healthy Subjects Under Fasting Conditions
- Bioavailability Comparison of Teriflunomide 14 mg Film-Coated Tablets: Single-Dose, Open-Label, Randomized Crossover Study in Healthy Subjects Under Fasting Conditions
- Bioavailability Study of Diclofenac 2.32% Gel in Healthy Adults
Data & Insights
Has run more than one trial at 1 of 1 partner site.
Specializations
Oncology
The investigator focuses on refractory solid tumors including advanced endometrial carcinoma, unresectable hepatocellular carcinoma, and radioiodine‑refractory differentiated thyroid carcinoma.
- Advanced endometrial carcinoma
- Unresectable hepatocellular carcinoma
- Radioiodine‑refractory thyroid carcinoma
- Targeted kinase inhibitor evaluation
Therapeutic strategies aim at patients unsuitable for curative surgery or radiation.
Immunology and Hematology
Research includes bone‑marrow failure and myeloproliferative conditions such as aplastic anemia, Philadelphia‑positive chronic myeloid leukemia, and thrombocytopenia.
- Aplastic anemia
- Philadelphia‑positive chronic myeloid leukemia
- Thrombocytopenia
- Leukemia cell line investigations
Efforts target innovative therapies for hematologic malignancies and cytopenias.
Allergy and Dermatology
Active interest lies in hypersensitivity disorders, notably allergic rhinitis and urticaria.
- Allergic rhinitis
- Urticaria
- Allergy immunotherapy assessment
- Cutaneous mast‑cell activation studies
The work supports development of agents that modulate IgE‑mediated pathways.
Metabolic and Endocrine Disorders
Investigations cover chronic metabolic conditions such as type 2 diabetes mellitus and hormonal deficiencies like male hypogonadism.
- Type 2 diabetes mellitus
- Male hypogonadism
- Glucose‑lowering therapy bioequivalence
- Hormone replacement pharmacokinetics
Focus is placed on optimizing therapeutic exposure in these patient groups.
Neurology and Psychiatry
The investigator addresses central nervous system diseases including multiple sclerosis, schizophrenia, and nicotine addiction.
- Multiple sclerosis
- Schizophrenia
- Nicotine addiction
- Neuropharmacologic safety profiling
Research aims to improve disease‑modifying and symptom‑control treatments.
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